Lazio will be looking to bounce back from their disappointing run of form when they welcome Genoa to the Stadio Olimpico on Friday in the Serie A.
The home side’s season continues to drift off course, with their recent 0-0 stalemate against relegation-battling Lecce extending a worrying run of form. They have now managed just one win from their last seven Serie A matches.
Even without the demands of European competition, the prospect of finishing outside the top six for a second consecutive season, something they have not done in over ten years, is becoming increasingly realistic.
Their struggles are particularly evident at the Olimpico, where Lazio are without a league victory in five games, failing to find the net in three of their last four.
Genoa, by contrast, arrive with renewed confidence after extending their unbeaten run to five matches. Their latest outing saw them overturn a two-goal deficit to secure an impressive 3-2 win over Bologna, a result that pushed them six points clear of the relegation zone.
Despite that momentum, consistency against stronger opposition has been elusive, with that victory standing as their only win against teams currently in the top nine.
Their away form further underlines the challenge they face, having recorded just two league wins on the road this season, while defensive fragility remains an issue after managing only one away clean sheet in Serie A.
Read our Lazio vs Genoa predictions and preview to find out, and remember to check our other Italian Serie A predictions.
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Lazio vs Genoa prediction: Home to win the game
Key statistics
- Lazio are unbeaten in their last five meetings against Genoa.
- They have not played BTTS in their last five encounters.
- The home team have won four of their last home clashes with the visitors.
Correct score prediction: Lazio 2-0 Genoa
We expect the home team to secure a comfortable victory in this Friday night clash. We predict a 2-0 win for Lazio based on their superior individual quality and their strong record when hosting Genoa at the Stadio Olimpico.
The Biancocelesti have often found a way to break through stubborn defences at home, and with the creative spark provided by their midfield, they should create enough high-quality chances to win.
While Genoa are compact and coming off a high-scoring win, we believe the pressure from the home crowd and the tactical flexibility of Baroni will eventually see the host find the back of the net twice without reply.
Pre-match odds and win probability: Lazio are slight favourites
- Home: 10/11 (1.91) – 52.4%
- Draw: 11/5 (3.20) – 31.3%
- Away: 10/3 (4.33) – 23.1%
*Odds provided by Ladbrokes. Subject to change.*
The bookmakers make Lazio clear favourites for this encounter, with odds of 1.91 suggesting a 52.4% chance of a home win. The draw is priced at 3.20, implying a 31.3% probability.
Genoa are considered the weaker team at 4.33 odds, giving them a 23.1% chance of taking all three points. The market leans towards a Lazio victory, but leaves room for a competitive contest.
Most recent head-to-head: Lazio’s dominance
Lazio have enjoyed a very successful run against Genoa in their most recent competitive encounters. Looking at the last five head-to-head meetings, the Biancocelesti have emerged victorious on five occasions.
The most recent meeting in September 2025 ended in a convincing 3-0 away win for Lazio, which followed a 2-0 victory earlier in April of the same year. Even when the matches have been played in Rome, the host have typically dominated, including a 3-0 win in late 2024.
Italy Serie A 29/09/25
Genoa
Lazio
Italy Serie A 23/04/25
Genoa
Lazio
Italy Serie A 27/10/24
Lazio
Genoa
Italy Serie A 19/04/24
Genoa
Lazio
Coppa Italia 05/12/23
Lazio
Genoa
After reviewing our key Lazio vs Genoa predictions, be sure to visit our website for the remaining football betting tips today.
Lazio preview: Squad changes and fitness concerns
Lazio have seen several departures from their squad, most notably Greek goalkeeper Christos Mandas, who recently joined Bournemouth.
In response, the Biancocelesti have added Kenneth Taylor and Petar Ratkov, with Italy international Daniel Maldini arriving on an initial loan from Atalanta. Maldini could be in line to feature on Friday, especially with Lazio’s attack struggling for consistency this season.
In terms of availability, Samuel Gigot and Patric remain sidelined through injury, while Nicolo Rovella is still working his way back to full fitness after a lengthy absence.
Predicted lineup: Provedel (GK), Lazzari, Gila, Romagnoli, Marusic, Basic, Cataldi, Taylor, Cancellieri, Ratkov & Zaccagni
Last five fixtures
- 24.01.26 – Lecce 0–0 Lazio
- 19.01.26 – Lazio 0–3 Como
- 11.01.26 – Verona 0–1 Lazio
- 07.01.26 – Lazio 2–2 Fiorentina
- 04.01.26 – Lazio 0–2 Napoli
Genoa preview: Return boost amid absentees
Genoa will be without Albert Gronaek, Benjamin Siegrist, and recent loan signing Tommaso Baldanzi, who joined from Roma.
However, there is some positive news for the visitors, as goalscoring defender Leo Ostigard returns to contention after completing a one-match suspension. His availability could see Sebastian Otoa drop out of the starting XI.
Predicted lineup: Leali (GK), Marcandalli, Ostigard, Vasquez, Norton-Cuffy, Frendrup, Malinovskyi, Ellertsson, Martin, Vitinha & Colombo
Last five fixtures
- 25.01.26 – Genoa 3–2 Bologna
- 18.01.26 – Parma 0–0 Genoa
- 12.01.26 – Genoa 3–0 Cagliari
- 08.01.26 – AC Milan 1–1 Genoa
- 03.01.26 – Genoa 1–1 Pisa
Player to watch: Mattia Zaccagni
Mattia Zaccagni is the player to watch for the home side as he continues to be the primary creative force for the Biancocelesti. The Italian international has recorded three goals and several key contributions in his most recent performances.
The winger has been central to the attacking rhythm of the team by winning many fouls and creating high-quality chances for his teammates. He has maintained a high level of performance by using his dribbling ability to bypass defenders and deliver dangerous crosses into the box.