Sparks will fly as Lazio and Cagliari draw swords in the 10th round of Serie A at Stadion Olimpico on Monday, 3 November 2025.
View our free Lazio vs Cagliari predictions below.
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Lazio vs Cagliari predictions: Hosts to reign supreme
Key stats
- Lazio have 11 wins in their last 12 encounters with Cagliari.
- Cagliari are currently on a five-match winless streak.
- Five of the last six clashes between these sides went above the 2.5-goal threshold.
Correct score prediction: Lazio 2-1 Cagliari
These teams are on opposite sides in terms of recent form. On one hand, Lazio have strung together a five-match unbeaten run, keeping four clean sheets. They are up against a Cagliari side on a five-game winless run.
Moreover, Lazio came out on top the last five times these teams clashed. They have dominated Cagliari in the past, winning 11 of the last 12 H2Hs.
All things considered, Lazio should win.
Pre-game odds and win probability: Lazio are clear favourites
- HOME: 8/13 (1.62) – 61.9%
- DRAW: 27/10 (3.70) – 27%
- AWAY: 21/4 (6.25) – 16%
*Odds from Ladbrokes, subject to change
Cagliari suffered their third consecutive home defeat when they faced Sassuolo a few days ago. Fabio Pisacane’s men have not particularly had a great campaign so far, having won only two of nine Serie A games.
On the other hand, Lazio's goalless draw against Pisa was their third stalemate in four games. The hosts have been able to rely on their solid defence, keeping four clean sheets in their last five matches.
Ahead of this encounter, Lazio and Cagliari are 12th and 14th in Serie A, respectively.
With that in mind, Lazio are the expected winners at 8/13 (1.62). Teams with these odds generally have a 61.9% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Lazio vs Cagliari predictions.
Also, keeping in mind that five of the last six clashes between these sides went above the 2.5-goal line, over 2.5 total goals has an appealing look at 1/1 (2.00). That one has a 50% chance of landing.
Most recent H2Hs: Business as usual for Lazio?
It is safe to say that Cagliari do not particularly look forward to meeting Lazio, as they have no wins in 20 consecutive encounters between these teams (D3, L17), stretching back to May 2013.
Italy Serie A 03/02/25
Cagliari
Lazio
Italy Serie A 04/11/24
Lazio
Cagliari
Italy Serie A 10/02/24
Cagliari
Lazio
Italy Serie A 02/12/23
Lazio
Cagliari
Italy Serie A 05/03/22
Cagliari
Lazio
Lazio preview: Plagued by injuries
Head coach Maurizio Sarri will be greatly short-handed while picking his team for this clash due to an injury crisis, as up to eight players are ruled out, including Nuno Tavares (muscle), Samuel Gigot (ankle), Valentin Castellanos (thigh), Fisayo Dele-Bashiru (thigh problem), Nicolo Rovella (groin), Matteo Cancellieri (thigh), Dimitrije Kamenovic (groin), and Elseid Hysaj.
Predicted lineup: Provedel (GK), Lazzari, Gila, Romagnoli, Marusic, Guendouzi, Cataldi, Vecino, Isaksen, Dia & Zaccagni.
Last five matches
- Pisa 0-0 Lazio
- Lazio 1-0 Juventus
- Atalanta 0-0 Lazio
- Lazio 3-3 Torino
- Genoa 0-3 Lazio
Cagliari preview: Hoping to halt their unwanted streak
Similarly, there are several injury worries for Cagliari ahead of this contest. Experienced striker Andrea Belotti is ruled out for much of the season due to a cruciate ligament injury. Marco Rog and Boris Radunovic have calf problems; Nicola Pintus is sidelined with a groin injury, Alessandro Deiola is out due to thigh concerns, while Adam Obert misses out through suspension (accumulated yellow cards).
Predicted lineup: Caprile (GK), Idrissi, Mina, Pedro, Palestra, Folorunsho, Prati, Adopo, Gaetano, Exposito & Borrelli.
Last five matches
- Cagliari 1-2 Sassuolo
- Verona 2-2 Cagliari
- Cagliari 0-2 Bologna
- Udinese 1-1 Cagliari
- Cagliari 0-2 Inter
Player to watch: Mattia Zaccagni
Although Mattia Zaccagni has scored only twice in Serie A this season, he has a solid track record against Cagliari, with three goal contributions in the last two clashes between these sides. It will be interesting to see how the former Hellas Verona midfielder will perform on Monday night.