AC Milan will face a difficult trip to take on Lazio at the Stadio Olimpico on Thursday in the Coppa Italia, with both teams seeking a spot in the next round of the competition.
The home side enter this match following a decent run of form, with two wins, one draw and two losses. They failed to build on their win against Lecce and suffered a disappointing 1-0 loss against AC Milan in their last league game.
The visiting team are enjoying a far more consistent run and are unbeaten in their last five games, with three wins and two draws. Their last match was a narrow 1-0 home victory against Lazio, a huge morale boost for this clash.
Read our Lazio vs AC Milan predictions and preview to find out, but remember to also check Coppa Italia predictions
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Lazio vs AC Milan prediction: The visitors to claim narrow win
Key statistics
- AC Milan have won three of their last five meetings against Lazio.
- Their last two meetings ended with both teams scoring.
- Lazio have played over 2.5 goals against AC Milan in four of their last five home games.
Correct score prediction: Lazio 1-2 AC Milan
For this clash, we anticipate a tight match, but we tip the visitors to come out with a narrow win. AC Milan have been particularly strong defensively; however, Lazio’s tendency to perform well at home makes it a tight affair.
Given the competitive nature of cup football, we believe both teams will cancel each other out by scoring against each other, but we believe the visitors will nick a win, with a prediction of a 2-1 victory for AC Milan.
Pre-match odds and win probability: AC Milan are slight favourites
- Home: 9/4 (3.25) – 30.8%
- Draw: 12/5 (3.40) – 29.4%
- Away: 23/20 (2.15) – 46.5%
*Odds provided by Ladbrokes. Subject to change.*
With the odds provided, AC Milan hold a narrow edge at 2.15 odds, giving them a 46.5% implied chance of victory. Lazio are priced at 3.25 (30.8%), making them competitive but still underdogs, while the draw at 3.40 (29.4%) suggests a tight game is expected.
Most recent head-to-head: AC Milan edge record
The last five competitive meetings between Lazio and AC Milan show a very balanced outcome, though the Rossoneri have a slight edge. In those games, the Rossoneri have secured three victories, while Lazio has won once, with one match ending in a draw.
Their recent meeting ended in a 2-1 loss for AC Milan in 2025 and a 2-2 draw in 2024. The last time the Rossoneri won was a 0-1 victory in March 2024. They will be looking to get a win over the home team in this clash.
Italy Serie A 29/11/25
AC Milan
Lazio
Italy Serie A 02/03/25
AC Milan
Lazio
Italy Serie A 31/08/24
Lazio
AC Milan
Italy Serie A 01/03/24
Lazio
AC Milan
Italy Serie A 30/09/23
AC Milan
Lazio
After reviewing our key Lazio vs AC Milan predictions, be sure to visit our website for the remaining football betting tips today.
Lazio preview: Some key players are injured
Lazio will be missing Samuel Gigot, Danilo Cataldi, Nicolo Rovella and Matteo Cancellieri, all sidelined through injury. Their absences leave gaps in both defence and midfield, which could force the manager to rotate his team and rely on less-experienced options.
Predicted lineup: Mandas (GK), Lazzari, Patric, Romagnoli, Tavares, Guendouzi, Belahyane, Basic, Pedro, Noslin & Zaccagni
Last five fixtures
- 29.11.25 – AC Milan 1–0 Lazio
- 23.11.25 – Lazio 2–0 Lecce
- 09.11.25 – Inter 2–0 Lazio
- 03.11.25 – Lazio 2–0 Cagliari
- 30.10.25 – Pisa 0–0 Lazio
AC Milan preview: Visitors struggling with new injuries
Milan, meanwhile, will be without Zachary Athekame, Christian Pulisic, and Santiago Gimenez. The trio’s absence limits attacking options and could disrupt the team’s usual fluidity in the final third. This leaves Massimiliano Allegri with no option but to rotate and make some changes for this game
Predicted lineup: Maignan (GK), Tomori, Gabbia, Pavlovic, Saelemaekers, Ricci, Modric, Rabiot, Estupinan, Nkunku & Leao
Last five fixtures
- 29.11.25 – AC Milan 1–0 Lazio
- 23.11.25 – Inter 0–1 AC Milan
- 08.11.25 – Parma 2–2 AC Milan
- 02.11.25 – AC Milan 1–0 AS Roma
- 28.10.25 – Atalanta 1–1 AC Milan
Player to watch: Rafael Leao
Rafael Leao is the player we identify as the one to watch, primarily because he is the most dangerous attacking option for AC Milan and is likely to be important in the visitors’ attack.
This season, Leao has shown his ability to penetrate defences and deliver crucial moments of quality. He has scored seven goals and provided two assists, making him an essential player for AC Milan’s progression in the cup.