Inter will face Lecce at the Stadio Giuseppe Meazza this Wednesday as the Nerazzurri aim to cement their position at the summit of the Serie A table.
Inter let a commanding position slip on Sunday by surrendering the lead twice in a 2–2 draw with Napoli, yet the result was enough to keep them three points clear at the summit heading into midweek action.
That stalemate was their first draw of the league campaign and only the second occasion this season in which they failed to win after opening the scoring. With both Milan and Napoli close behind in the title race, further slips could prove costly, making a quick response essential.
Encouragingly for the Nerazzurri, their home form remains strong, with only those two rivals managing to take points from their last eight league games at San Siro, suggesting they are well placed to bounce back.
Lecce, meanwhile, come into this fixture under growing pressure. They were beaten 2–1 by Parma at the weekend after throwing away a lead and ending the match with just nine players, a result that continued a worrying run of form.
With three defeats in their last four outings, Eusebio Di Francesco’s side sit only three points above the relegation places. Their cause is not helped by fragile away form, having lost five of their last eight matches on the road in all competitions.
Read our Inter vs Lecce predictions and preview to find out, but remember to also check our other Serie A predictions.
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Inter vs Lecce prediction: Home team to claim a comfortable win
Key statistics
- BTTS has not been played in their last five meetings.
- Inter have won their last five encounters with Lecce.
- Martinez is on a scoring spree, with four goals in his last five league games.
Correct score prediction: Inter 3-0 Leece
We expect the home team to dominate this contest from start to finish and secure a comfortable victory. We predict a 3–0 win for Inter, as the Nerazzurri have demonstrated immense finishing throughout 2026.
The gap in quality between the league leaders and a struggling Lecce side is significant, especially considering the home side has kept three clean sheets in their last five league games.
Pre-match odds and win probability: Inter heavy home favourites
- Home: 2/11 (1.18) – 84.6%
- Draw: 13/2 (7.50) – 13.3%
- Away: 14/1 (15.00) – 6.7%
*Odds provided by Ladbrokes. Subject to change.*
Heading into this fixture, the bookmakers strongly favour Inter at 1.18, which implies an 84.6% chance of a home victory. Lecce are priced at a distant 15.00 (6.7%) to spring a major upset, while the draw is available at 7.50 (13.3%). The odds reflect Inter’s dominance at home and the clear gap in quality between the two sides going into this fixture.
Most recent head-to-head: Inter dominate encounter
Looking at the history between these two clubs, the last five competitive meetings reveal a clear pattern of dominance for the Nerazzurri. Across these last five fixtures, Inter has claimed five victories without conceding a goal.
In recent years, the Giallorossi have struggled even to find the back of the net against the Milanese side, failing to score in four of their last five attempts. Their last meeting ended in a 4-0 win in the first leg for Inter and a 2-0 win in the second leg.
Italy Serie A 21/12/25
Inter Milan
Lecce
Italy Serie A 26/01/25
Lecce
Inter Milan
Italy Serie A 24/08/24
Inter Milan
Lecce
Italy Serie A 25/02/24
Lecce
Inter Milan
Italy Serie A 23/12/23
Inter Milan
Lecce
After reviewing our key Inter vs Lecce predictions, be sure to visit our website for the remaining football betting tips today.
Inter preview: Home team battling with Injuries
Inter will have to cope with several absences for this fixture. Goalkeepers Josep Martinez and Raffaele Di Gennaro are both sidelined with injury, while Tomas Palacios is also unavailable.
The biggest concern is in the wing-back areas, as both Denzel Dumfries and Matteo Darmian are ruled out through injury, limiting Simone Inzaghi’s options out wide.
Predicted lineup: Sommer (GK), Bisseck, Akanji, Bastoni, Luis Henrique, Barella, Calhanoglu, Zielinski, Dimarco, Thuram & Martinez
Last five fixtures
- 11.01.26 – Inter 2–2 Napoli
- 07.01.26 – Parma 0–2 Inter
- 04.01.26 – Inter 3–1 Bologna
- 28.12.25 – Atalanta 0–1 Inter
- 19.12.25 – Bologna 2–1 Inter
Lecce preview: Long injury list and suspensions
Lecce arrive significantly depleted, with a mix of injuries and suspensions affecting the squad. Francesco Camarda, Gaby Jean, Tete Morente, Christian Fruchtl, Balthazar Pierret and Medon Berisha are all unavailable due to injury.
On top of that, Kialonda Gaspar and Lameck Banda will miss out through suspension, further weakening Di Francesco’s side for this tough away assignment.
Predicted lineup: Falcone (GK), Veiga, Siebert, Tiago Gabriel, Ndaba, Kaba, Ramadani, Maleh, Pierotti, Stulic & N’Dri
Last five fixtures
- 11.01.26 – Lecce 1–2 Parma
- 06.01.26 – Lecce 0–2 AS Roma
- 03.01.26 – Juventus 1–1 Lecce
- 27.12.25 – Lecce 0–3 Como
- 12.12.25 – Lecce 1–0 Pisa
Player to watch: Lautaro Martinez
Lautaro Martinez continues to be the key player in the Inter Milan team and has established himself as one of the league’s standout performers. He is currently the top scorer in Serie A for his team and has scored 10 goals and provided four assists.
With Inter looking to maintain their position at the top of the table, much of their attacking threat is expected to flow through the Argentine, who will be looking to add to his goal tally this season.