Inter Miami vs Seattle Sounders prediction, odds & betting tips – 17/09/2025
Fireworks expected as Inter Miami and Seattle Sounders renew hostilities - Photo by IMAGO
🔥 Our Hot tip

Inter Miami to win

Having now lost consecutive matches for the first time since May, Inter Miami will head into this one in need of a lift, and their imperious home form should offer some cause for optimism. We are backing them to just about do enough to fend off the challenge of Seattle and secure a return to winning ways.

Inter Miami and Seattle Sounders will go head-to-head for the second time in just over two weeks in Wednesday's Major League Soccer meeting at the Chase Stadium.

The hosts will be keen to get one over the away side after their Leagues Cup defeat, and we will be previewing what promises to be a feisty affair in this Inter Miami vs Seattle Sounders prediction article.

Inter Miami vs Seattle Sounders prediction: Lionel Messi and co to emerge victorious

Key stats

  • Inter Miami's most recent 3-0 demolition was in keeping with their recent defensive frailties, as they have now gone 10 straight matches without a clean sheet.
  • However, the Herons have scored in all but two of those matches, and this has seen nine of the 10 games produce at least three goals.
  • While the Seattle Sounders will be disappointed not to have extended their winning streak last time out, they are now unbeaten in five matches, picking up four wins and a draw.
  • Wednesday's visitors have profited handsomely from flying out of the blocks, having opened the scoring in four of their last five outings.

Correct score prediction: Inter Miami 2-1 Seattle Sounders

Having now lost consecutive matches for the first time since May, Inter Miami will head into this one in need of a lift, and their imperious home form should offer some cause for optimism.

We are backing them to just about do enough to fend off the challenge of Seattle and secure a return to winning ways.

Pre-game odds and win probability: Hosts backed to exact revenge

  • HOME: 10/11 (1.91) – 52.4%
  • DRAW: 5/2 (3.50) – 28.6%
  • AWAY: 11/5 (3.20) – 31.3%

*Odds from Ladbrokes, subject to change

An Inter Miami win is priced at 1.91 with a 52.4% probability, suggesting the home side are favourites to come away with maximum points, although they will need to shake off a disappointing defeat against Charlotte FC last time out.

After fluffing a glorious opportunity to open the scoring from the spot through Lionel Messi, Javier Mascherano's men were made to pay down the other end almost immediately as Idan Toklomati broke the deadlock before adding two more in the second half to complete a superb hat-trick.

Seattle have not tasted defeat in nearly a month, but Brian Schmetzer's men have been given only a 31.3% chance of getting the job done here.

The Rave Greens looked set for a fifth straight win after taking a commanding two-goal lead against LA Galaxy thanks to Jesus Ferreira and Daniel Musovski, before Maya Yoshida and Miki Yamane scored in either half to force a share of the spoils.

For more from the upcoming matches, today’s free football betting tips look at some of the best picks.

Most recent H2Hs: All-square after two

While the recent final was the most notable meeting between Wednesday's opponents, it was only the second edition of this fixture after the first instalment in 2021, which Inter Miami won 1-0.

However, Seattle ran riot en route to Leagues Cup glory earlier this month after a comprehensive 3-0 win at Lumen Field.

Leagues Cup 01/09/25

Seattle Sounders

Seattle Sounders

3
Inter Miami CF

Inter Miami CF

0

USA MLS 17/04/22

Seattle Sounders

Seattle Sounders

0
Inter Miami CF

Inter Miami CF

1

Inter Miami preview: Tomas Aviles adds to suspension issues

With Luis Suarez already suspended for his misconduct in the aftermath of Inter Miami's Leagues Cup final defeat, Aviles is also ineligible to feature for the Herons after he received his marching orders against Charlotte.

Allen Obando, Fafa Picault and Baltasar Rodriguez are all sidelined and will not play any part for the hosts.

Predicted lineup: Ustari(GK), Alba, Falcon, Lujan, Fray, Segovia, Busquets, Bright, De Paul, Allende & Messi

Inter Miami's last five matches:

  • Charlotte 3-0 Inter Miami (MLS)
  • Seattle Sounders 3-0 Inter Miami (Leagues Cup)
  • Inter Miami 3-1 Orlando City (Leagues Cup)
  • DC United 1-1 Inter Miami (MLS)
  • Inter Miami 2-1 Tigres UANL (Leagues Cup)

Seattle Sounders preview: Pedro de La Vega on the brink of return

Pedro de La Vega missed Seattle's last outing with a knee problem, and while Wednesday's affair is expected to come too soon for the Argentine forward, he is edging closer towards a comeback.

Also sidelined with knee issues are Joao Paulo and Paul Arriola, as Stuart Hawkins and Ryan Kent continue to nurse thigh and muscle injuries respectively.

Predicted lineup: Frei (GK), A Roldan, Ragen, Andrade, Baker-Whiting, C Roldan, Vargas, Kossa-Rienzi, Ferreira, Rothrock & Musovski

Seattle Sounders' last five matches:

  • Seattle Sounders 2-2 LA Galaxy (MLS)
  • Seattle Sounders 3-0 Inter Miami (Leagues Cup)
  • LA Galaxy 0-2 Inter Miami (Leagues Cup)
  • Seattle Sounders 5-2 Sporting Kansas City (MLS)
  • Seattle Sounders 0-0 (4-3 on pens) Puebla

Player to watch – Danny Musovski

Having been involved in both of Seattle's two goals against LA Galaxy, Musovski has now directly contributed to eight goals in his last six outings across all competitions.

With 14 league strikes already this term, the 29-year-old is enjoying the highest-scoring season of his career in his sophomore campaign at Lumen Field.

Danny Musovski converts a penalty for Seattle Sounders – Photo by IMAGO

Musovski was absent from the Leagues Cup final a fortnight ago when his team ran out 3-0 winners against Inter Miami, and he will be aiming to play a starring role here.


Trading in blueprints for bylines, Marvellous is an engineering graduate who has found his true calling in sports writing. A dedicated Chelsea fan who also follows the NBA, he enjoys blending his love for football and basketball with thoughtful commentary and a relatable voice that keeps readers connected.