Hoffenheim welcome Lyon to the PreZero Arena to contest a Europa League Group Stage clash on Thursday, 7 November. Read our Europa League predictions for the contest below.
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Hoffenheim vs Lyon prediction: Expect at goals at both ends
Key Stats
- Lyon have failed to score in only one of their last nine matches in all competitions.
- Five of Hoffenheim’s seven home games this term have featured goals at both ends.
- Lyon have lost only one of their last eight competitive assignments.
- Both Hoffenheim and Lyon have been winning an average of 6.00 corners per game in the Europa League this season.
Correct score prediction: Hoffenheim 2-2 Lyon
Hoffenheim have been hit and miss in the Europa League so far, though they have won three of their last four home games in all competitions, netting twice in three of those contests, so expect them to trade blows with Lyon.
Pre-game odds and win probability: Hoffenheim are slight underdogs
- HOME: 13/8 (2.63) – 38.1%
- DRAW: 13/5 (3.60) – 27.8%
- AWAY: 6/4 (2.50) – 40%
*odds from Ladbrokes, subject to change
Hoffenheim lost 2-0 at home to St Pauli in a surprise result at the weekend, while the Germans have won one, drawn one and lost one of their three UEL matches. That record makes their 13/8 price to win a little unattractive here.
Lyon meanwhile, won two of their first three Europa League group games and they have a 40% chance of winning again in Germany, according to the markets. Visit our football tips page for more Europa League predictions.
Most recent H2Hs: First meeting in six years
Hoffenheim and Lyon have met twice before and both encounters in the Champions League during the 2018/19 produced over 2.5 goals.
UEFA Champions League 07/11/18
Lyon
TSG Hoffenheim
UEFA Champions League 23/10/18
TSG Hoffenheim
Lyon
Hoffenheim preview: Six players sidelined
Christopher Lenz, Dennis Geiger, Grischa Promel, Ihlas Bebou, Finn Ole Becker and Ozan Kabak are out injured for Hoffenheim. The hosts limped to a disappointing 2-0 loss at home to St Pauli at the weekend and slipped down to 16th place in the Bundesliga shortly after.
Predicted lineup: Baumann (GK), Chaves, Stach, Nsoki, Gendrey, Grillitsch, Bischof, Prass, Kramaric, Hlozek, Bulter
Germany Bundesliga I 09/05/25
D
Wolfsburg
2
TSG Hoffenheim
2
Germany Bundesliga I 03/05/25
D
Borussia M'gladbach
4
TSG Hoffenheim
4
Germany Bundesliga I 26/04/25
L
Borussia Dortmund
3
TSG Hoffenheim
2
Germany Bundesliga I 19/04/25
L
SC Freiburg
3
TSG Hoffenheim
2
Germany Bundesliga I 12/04/25
W
Mainz
0
TSG Hoffenheim
2
Lyon preview: Diawara and Nuamah out
Mahamadou Diawara and Ernest Nuamah are in the treatment room and will miss Thursday's game. Lyon battled their way to a share of the spoils at Lille at the weekend thanks to an injury-time equalizer from Martin Fofana.
Predicted lineup: Perri (GK), Maitland-Niles, Caleta-Carr, Niakhate, Tagliafico, Veretout, Matic, Tolisso, Cherki, Fofana, Lacazette
France Ligue 1 10/05/25
L
Monaco
2
Lyon
0
France Ligue 1 04/05/25
L
Lens
2
Lyon
1
France Ligue 1 26/04/25
W
Rennes
1
Lyon
4
France Ligue 1 20/04/25
L
St Etienne
2
Lyon
1
UEFA Europa League 17/04/25
L
Man Utd
5
Lyon
4
Player to watch – Rayan Cherki
Rayan Cherki has been in electric form in the Europa League this season and the 21-year-old attacking midfielder has already lodged a goal and two assists in just three appearances in the competition so far.

Cherki can shine again
Cherki has been averaging a massive 4.70 key passes per game in the Europa League this season and the silky midfielder’s passing range could be a feature of Thursday’s clash in Germany.