Genoa and Lazio will go head-to-head in round five of the 2025-26 Serie A campaign on Monday, 29 September 2025 at Stadio Luigi Ferraris.
Genoa gave up a lead in their 2-1 loss to Bologna in their last outing, a result which extended their winless run to four games since the start of the season. Now, Patrick Viera and his charges will be wary of yet another defeat on Monday, as they will be looking to avoid a repeat of their start to the 2017-18 season, when they failed to win any of their first five fixtures.
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Genoa vs Lazio predictions: Lazio are on a four-game winning streak against the hosts
Key stats
- Genoa are without a win in their first four league fixtures.
- Lazio have managed only one in four Serie A fixtures this term.
- Lazio have beaten the hosts in four consecutive competitive fixtures.
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Correct score prediction: Genoa 0-2 Lazio
Genoa have endured a torrid start to the season, failing to win in their opening four league contests, and the home side will be in danger of equalling an unwanted record of five matches without a victory in the first five matches since the 2017-18 season.
However, Lazio are not too far away from the hosts in terms of results in the current campaign, having managed only one triumph and three losses in their first four encounters of the season. That said, they are still favourites to win on Monday and we are backing them to claim a 2-0 win.
Pre-game odds and win probability: Lazio are in the ascendancy
- HOME: 19/10 (2.90) – 34.5%
- DRAW: 21/10 (3.10) – 32.3%
- AWAY: 29/20 (2.45) – 40.8%
*Odds from Ladbrokes, subject to change
While both teams have endured a difficult start to this campaign, Lazio are still regarded as the side with the better chances of going home with all three points when they clash on Monday evening. According to the bookies, Lazio are priced at 29/20 (2.45), a 40.8% probability of winning.
For the home side, the odds are 19/10 (2.90), which translates to a chance of 34.5% to claim all three points. For a draw, there are 21/10 (3.10) odds for this contest to end in a stalemate, and there is a 32.3% chance of that happening.
Don’t forget to check out more of our best betting tips for other leagues.
Most recent H2Hs: Lazio are in search of their fifth win against the hosts
Lazio have been the better side by a country mile in meetings between these teams. Their record of four victories in five contests against the home side is an indicator of how well the visitors have fared against the hosts.
Going into this encounter, the away side will be full of confidence, and it is well within their rights to dream of a fifth win in six meetings against the home side.
Italy Serie A 23/04/25
Genoa
Lazio
Italy Serie A 27/10/24
Lazio
Genoa
Italy Serie A 19/04/24
Genoa
Lazio
Coppa Italia 05/12/23
Lazio
Genoa
Italy Serie A 27/08/23
Lazio
Genoa
Genoa preview: Genoa are in dire straits
Genoa are in a desperate situation, and they will be hard-pressed to fashion a win on Monday, despite their disadvantages. However, they will be playing in front of their fans, and they are expected to get massive support from their vociferous supporters.
Nevertheless, Jean Onana is out with an unspecified injury, and he will not be in Vieira's plan for Monday's fixture.
Predicted lineup: Leali (GK), Martin, Vazquez, Ostigard, Norton-Cuffy, Masini, Frendrup, Ellertsson, Malinovsky, Carboni & Carboni
Last five matches
- Genoa 3-1 Empoli
- Bologna 2-1 Genoa
- Como 1-1 Genoa
- Genoa 0- 1 Juventus
- Genoa 0- 0 Lecce
Lazio preview: Can Lazio keep up their dominance?
Despite their unimpressive start to the current season, the visiting side will come into this contest with a psychological advantage, having won four consecutive matches against the home side.
Nevertheless, they have a few injury and suspension issues to deal with ahead of Monday's contest, as Matteo Guendouzi is suspended, along with Reda Belahyane.
Nicolo Rovella is out with an inflammation of the pubic bone, while Fisayo Dele-Bashiru and Manuel Lazzari are out with hamstring and calf injuries, respectively.
Predicted lineup: Provedel (GK), Marusic, Gila, Romagnoli, Tavares, Cataldi, Basic, Zaccagni, Cancellieri, Castellanos & Dia
Last five matches
- Lazio 0-1 AS Roma
- Sassuolo 1-0 Lazio
- Lazio 4-0 Verona
- Como 2-0 Lazio
- Lazio 2-0 Atromitos
Player to watch: Valentin Castellanos
Valentin Castellanos has been one of the most consistent players in the blue half of Rome in the past few years. Since the previous season and the start of the current campaign, he has always been one of the first names on the team sheet.
With his work rate and eye for goal, the Genoa defenders have to be at their best for the entire duration of this fixture.
