Frankfurt vs Liverpool prediction, odds & betting tips 22/10/2025
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Frankfurt or draw

Frankfurt are unbeaten in their last four matches against English sides at home.

Liverpool will take on Frankfurt in the Champions League this week, with the Reds looking to end their current four-match losing streak.

Arne Slot is under pressure for the first time since he became Liverpool manager in 2024, but a win on Wednesday night could go a long way to relieving some of that.

Frankfurt have made a decent start to the season in Germany, but after losing 5-1 to Atletico Madrid last time out in the Champions League, they are in need of a response.

As part of this week's round of Champions League betting tips, check out our Frankfurt vs Liverpool prediction below.

Frankfurt vs Liverpool prediction: Liverpool to drop more points

Key Stats

  • Liverpool lost their previous Champions League away match this season.
  • Frankfurt won their previous Champions League home match this season.
  • Both teams have scored in eight of Frankfurt's last nine matches.

Correct score prediction: Frankfurt 1-1 Liverpool

Frankfurt will fancy their chances of getting more than just a draw on Wednesday, but Liverpool's losing streak has to end at some point, and they will surely respond after losing to their bitter rivals, Man Utd, on Sunday.

Pre-game odds and win probability: Liverpool start as favourites

  • HOME: 19/5 (4.80) – 20.8%
  • DRAW: 7/2 (4.50) – 22.2%
  • AWAY: 3/5 (1.60) – 62.5%

*odds from Ladbrokes, subject to change

The Frankfurt vs Liverpool odds are still strongly weighted in favour of Liverpool, with the bookies not taking too much notice of their recent losing slump. Ladbrokes have given Frankfurt just a 20.8% chance of winning the match, while Liverpool have been given a 62.5% chance of victory.

You can find all our predictions for today's games on our football betting tips page.

Most recent H2Hs: A first meeting in over 50 years

Frankfurt and Liverpool haven't played each other since 1972, which adds an extra layer of intrigue to the fixture.

Frankfurt preview: A healthy squad

Frankfurt are in good nick coming into this match, with their only injury concern being teenage defender, Elias Braum. As a result, they will give this match a proper go, and a lot could rest on how Can Uzun and Jonathan Burkadt exploit the space behind the Liverpool back line.

Predicted lineup: Santos (GK), Kristensen, Koch, Theate, Brown, Skhiri, Larsson, Doan, Uzun, Bahoya, Burkardt

Last five results

  • Freiburg 2-2 Frankfurt
  • Frankfurt 0-3 Bayern Munich
  • Atletico Madrid 5-1 Frankfurt
  • Monchengladbach 4-6 Frankufrt
  • Frankfurt 3-4 Union Berlin

Liverpool preview: Problems in forward areas

Trying to find room for all of his big-money signings is proving to be a difficult task for Arne Slot. Former Frankfurt man, Hugo Ekitike, is expected to come back into the starting XI here, as is Florian Wirtz, who will perhaps be more comfortable against Bundesliga opposition. Alisson remains unavailable through injury.

Predicted lineup: Mamardashvili (GK), Bradley, Gomez, Van Dijk, Robertson, Jones, Szoboszlai, Frimpong, Wirtz, Gakpo, Ekitike

Last five results

  • Liverpool 1-2 Man Utd
  • Chelsea 2-1 Liverpool
  • Galatasaray 1-0 Liverpool
  • Crystal Palace 2-1 Liverpool
  • Liverpool 2-1 Southampton

Player to watch: Hugo Ekitike

Hugo Ekitike – Photo by IMAGO/Propaganda Photo

After spending north of £400m in the summer, the only summer recruit at Liverpool who is living up to the billing so far is Hugo Ekitike. The forward, who will be looking forward to playing against his former employers, has scored four goals and provided one assist in all competitions so far for the Reds.

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Andy is a freelance Sports Journalist with ten years of experience covering football in the United Kingdom and abroad for various publications including the Manchester Evening News, UtdReport and Football Whispers. Andy also has a keen interest in basketball, cricket, golf and tennis and has covered major sporting events such as the Masters in Augusta.