Juventus are targeting a place in the last four of the Coppa Italia on Wednesday night. Our Juventus vs Empoli prediction and betting tips consider whether they can see off their struggling opponents in Turin.
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Juventus vs Empoli prediction: Kolo Muani to score in easy home win
Key stats
- Our Juventus vs Empoli betting tips take into account that the visitors have lost six of their last seven overall, with all of those defeats coming by at least two goals.
- Juventus have won all three home games so far this month, including a 4-1 league win over Empoli.
- Five of their last seven home victories have come via two or more goals.
Correct score prediction: Juventus 3-0 Empoli
Even allowing for a bit of rotation, Juventus should be much too strong for a woefully out-of-form Empoli side here.
The visitors have taken just two points from their last 11 games in Serie A. They have problems at both ends of the pitch which the home team should exploit here.
Pre-game odds and win probability: Juve the red hot favourites
- HOME: 3/10 (1.30) – 76.9%
- DRAW: 17/4 (5.25) – 19.0%
- AWAY: 9/1 (10.00) – 10.0%
*odds from Ladbrokes, subject to change
The hosts are the favourites according to the Juventus vs Empoli odds, with an implied probability of 76.9% that they win this match.
They head into the game following a 1-0 win at Cagliari in Serie A, with Dusan Vlahovic grabbing the only goal.
As for Empoli, they hit a fresh low on Sunday, going down 5-0 at home to Atalanta with Emmanuel Gyasi’s own goal contributing to their demise.
For more from the upcoming matches in Europe, today’s free football betting tips look at some of the best picks.
Most recent H2Hs: Hosts unbeaten in four
Our Juventus vs Empoli prediction suggests the home team should easily extend a four-game unbeaten run, with a repeat of their recent three-goal victory possible.
Juventus have won four of the last six meetings in Turin, with Empoli’s last win here coming in 2021.
Italy Serie A 02/02/25
Juventus
Empoli
Italy Serie A 14/09/24
Empoli
Juventus
Italy Serie A 27/01/24
Juventus
Empoli
Italy Serie A 03/09/23
Empoli
Juventus
Italy Serie A 22/05/23
Empoli
Juventus
Juventus preview: Defensive problems continue
There are problems at the back for Juve, with Nicolo Savona, Renato Veiga, Bremer and Pierre Kalulu all currently out. Forward Arkadiusz Milik and midfielder Douglas Luiz are also injury doubts.
Predicted Lineup: Perin (GK), Weah, Gatti, Kelly, Rouhi, Thuram, Gonzalez, Koopmeiners, McKennie, Mbangula & Kolo Muani
Italy Serie A 10/05/25 D Lazio 1 Juventus 1 Italy Serie A 04/05/25 D Bologna 1 Juventus 1 Italy Serie A 27/04/25 W Monza 0 Juventus 2 Italy Serie A 23/04/25 L Parma 1 Juventus 0 Italy Serie A 12/04/25 W Lecce 1 Juventus 2
Empoli preview: Injury woe for the visitors
It has been a miserable season on the injury front for Empoli, with four players currently recovering from ACL issues. Tino Anjorin, Jacopo Fazzini and Mattia Viti are also expected to be missing here due to injuries.
Predicted Lineup: Vasquez (GK), De Sciglio, Goglichidze, Cacace, Henderson, Sambia, Grassi, Maleh, Pezzella, Esposito & Colombo
Italy Serie A 10/05/25 W Parma 1 Empoli 2 Italy Serie A 04/05/25 L Lazio 1 Empoli 0 Italy Serie A 27/04/25 L Fiorentina 2 Empoli 1 Coppa Italia 24/04/25 L Bologna 2 Empoli 1 Italy Serie A 20/04/25 D Venezia 2 Empoli 2 
Player to watch – Randal Kolo Muani
Randal Kolo Muani made a brilliant start to his Juventus career with five goals in his opening three appearances. That included a brace against Empoli, and he’s likely to rotate back into the starting lineup for this match.
Kolo Muani shining in Serie A
Since departing PSG, Kolo Muani has averaged a goal every 76 minutes in Serie A. Including his time in Ligue 1, he’s yet to score in the opening 30 minutes of a match this season, with 71% of his goals coming after the hour mark.