Como vs Manchester United prediction, preview & betting tips – 21/10/2026
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🔥 Our Hot tip

Como to win

Como have taken seven points from a possible nine at home this season.

Como will take on Manchester United in the UEFA Champions League on Wednesday, 21 October, with both teams looking to bounce back from defeats on matchday two.

Man Utd succumbed to a 2-0 defeat to Atletico Madrid, while Como lost 3-2 to Feyenoord.

Read our prediction, preview and betting tips for the game below, and make sure to check out our today's betting tips page for more of our expert predictions.

Como vs Man Utd key stats

  • Como have won five of their last eight matches in all competitions.
  • Man Utd have failed to win any of their last six matches in all competitions.
  • Ten goals have been scored across Como's two Champions League matches this season.

Como vs Man Utd preview: A memorable night ahead for the hosts

Como vs Man Utd — Tale of the Tape

Como vs Man Utd
5th (Serie A)Position13th (Premier League)
14Points7
12Goals For10
7Goals Against10
1Clean Sheets0
11thHome / Away Rank13th

There is an argument that Wednesday night is the biggest match in Como's history, at least in terms of the occasion and the opponent.

In what is their first-ever season in the UEFA Champions League, a home tie against one of the biggest clubs in the world would have been what everyone involved at Como would have wanted, and to make the situation even more exciting, they have a great chance of picking up all three points.

Cesc Fabregas' men are unbeaten at home in all competitions this season, and were excellent in their first Champions League match here last month, downing RB Leipzig 3-2.

Although their form has curtailed slightly in recent weeks, they picked up a confidence-boosting three points at the weekend, winning 3-1 away at Fiorentina.

Fabregas is sweating on the availability of Trevoh Chalobah and Moise Kean, but Assane Diao has been ruled out.

Another reason why the Italian side have a good chance of winning is Man Utd's form, which has seen them go six games without a win in all competitions.

Michael Carrick seemed happy enough with a point at Elland Road at the weekend, which may suggest his primary focus now is not losing games rather than going out and trying to win.

If United can win in Como on Wednesday night, it will be their first away win of the season, and could be a turning point. However, based on their performances over the course of the season so far, a win is unlikely.

Carrick is dealing with his fair share of injuries at present, with Manuel Ugarte, Patrick Dorgu and Benjamin Sesko out, Lisandro Martinez, Ayden Heaven and Kobbie Mainoo doubts, and Leny Yoro suspended.

Como vs Man Utd form guide & betting tips

Como vs Man Utd — Last 5 Form Guide
Como vs Man Utd
WLDLW
Form
LDDLD
7Goals For5
7Goals Against8
WL
UEFA Champions League
WL

Whispers predicts: Como 2-1 Man Utd

Como's strong away form, combined with United's winless streak, makes a Como win at 6/5 an excellent bet – one which you can make for free via this Betano promo code.

Fabregas has opened his Como side up in Europe, which could result in another end-to-end game. Over 2.5 goals has been priced at 1/2.

Anastasios Douvikas has scored three goals in his last four appearances for club and country. Douvikas to score anytime has been best priced at 6/4.

📈 Como vs Man Utd — Whispers' Tips

> Como to win at 6/5 (2.20) | Likelihood: High

> Over 2.5 goals at 1/2 (1.50) | Likelihood: High

> Douvikas to score anytime at 6/4 (2.50) | Likelihood: Medium

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Andy is a freelance Sports Journalist with ten years of experience covering football in the United Kingdom and abroad for various publications including the Manchester Evening News, UtdReport and Football Whispers. Andy also has a keen interest in basketball, cricket, golf and tennis and has covered major sporting events such as the Masters in Augusta.