Chile vs Argentina prediction, odds & betting tips – 5/6/2025
Julian Alvarez in action for Argentina - Photo by IMAGO.
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Argentina win to nil

Argentina lead the way in qualifying, while Chile are rock bottom, and have failed to score in nine of their 14 qualifiers for the 2026 World Cup

Argentina travel to Santiago to face Chile in 2026 World Cup qualifying on Thursday night. Lionel Scaloni's men have already booked their spot at the finals, while the hosts are in grave danger of missing out in a third successive World Cup.

Chile vs Argentina prediction: Fourth straight win in store for the Albiceleste

Key stats

  • Chile are one of just two nations yet to reach double figures for goals (nine) so far in CONMEBOL qualifying.
  • Argentina are unbeaten in eight matches against Chile, conceding only four goals in that time.
  • Chile have won just two of their 14 qualifiers for the 2026 World Cup.
  • Argentina enter this fixture on the back of a three-game winning streak, and no team has won more points on the road than them in World Cup qualifying (13).

Correct score prediction: Chile 0-2 Argentina

It has been a campaign to forget for Chile, and considering Bolivia came here and won earlier in the campaign, there is little down for them against the might of world champions Argentina, who are eight points clear at the top.

Pre-game odds and win probability: Visitors clear favourites with the bookmakers

  • HOME: 18/5 (4.60) – 21.7%
  • DRAW: 13/5 (3.60) – 27.8%
  • AWAY: 3/4 (1.75) – 57.1%

*odds from Ladbrokes, subject to change

It is very rare to see a team be such big favourites for an away match in South American qualifying, but that illustrates the gulf in class between these two sides.

Argentina are priced at 3/4 to take all three points in this one, which gives them an implied probability of 57.1% to do so, in what would be a fourth straight win for Scaloni's side.

Also, feel free to check out our expert predictions and football betting tips today.

Most recent H2Hs: Argentina looking to extend dominant run

Since losing the 2016 Copa America final to Chile, Argentina are unbeaten in eight games against La Roja, and they have only lost three competitive meetings against their upcoming opponents in their history, with a 3-0 win last year showcasing the step up in class among the Albiceleste squad.

South America - World Cup Qualifying 06/09/24

Argentina

Argentina

3
Chile

Chile

0

Copa America 26/06/24

Chile

Chile

0
Argentina

Argentina

1

South America - World Cup Qualifying 28/01/22

Chile

Chile

1
Argentina

Argentina

2

Copa America 14/06/21

Argentina

Argentina

1
Chile

Chile

1

South America - World Cup Qualifying 04/06/21

Argentina

Argentina

1
Chile

Chile

1

Chile preview: Faint hopes of a playoff spot

Hope is not yet lost for Chile, as they can still finish in seventh place, which would grant them a shot at the intercontinental playoffs, but it looks a tall order from this position, sitting five points behind Venezuela.

Manager Ricardo Gareca is also without key defender Paulo Diaz due to injury, while captain Alexis Sanchez has not enjoyed much game time at Udinese this season.

Predicted lineup: Cortes (GK), Loyola, Maripan, Sierralta, Suazo, Vidal, Echeverria, Pizarro, Osorio, Sanchez & Valdes

South America - World Cup Qualifying 26/03/25

D

Ecuador

Ecuador

0

Chile

Chile

0

South America - World Cup Qualifying 20/03/25

L

Paraguay

Paraguay

1

Chile

Chile

0

International Match 08/02/25

W

Panama

Panama

1

Chile

Chile

6

South America - World Cup Qualifying 20/11/24

W

Venezuela

Venezuela

2

Chile

Chile

4

South America - World Cup Qualifying 16/11/24

D

Peru

Peru

0

Chile

Chile

0

Argentina preview: Messi set to return

With qualification already secured, Scaloni can afford to experiment and try new ideas in their final four qualifiers, but one thing is for certain, and this is Lionel Messi will be in the starting XI on Thursday night.

Alexis Mac Allister will not be though, as the Liverpool man has pulled out with injury, joining Paulo Dybala and Lisandro Martinez on the sidelines.

Predicted lineup: E Martinez (GK), Molina, Romero, Otamendi, Tagliafico, De Paul, Enzo, Paredes, Messi, La. Martinez & Alvarez

South America - World Cup Qualifying 26/03/25

W

Brazil

Brazil

1

Argentina

Argentina

4

South America - World Cup Qualifying 21/03/25

W

Uruguay

Uruguay

0

Argentina

Argentina

1

South America - World Cup Qualifying 20/11/24

W

Peru

Peru

0

Argentina

Argentina

1

South America - World Cup Qualifying 14/11/24

L

Paraguay

Paraguay

2

Argentina

Argentina

1

South America - World Cup Qualifying 16/10/24

W

Bolivia

Bolivia

0

Argentina

Argentina

6

Player to watch: Lionel Messi

All eyes will be on Messi as he returns to the fold after missing March's qualifiers, and he brings excellent form into this one from MLS.

paraguay vs argentina predictions
Messi is in astonishing form at club level – Photo by IMAGO.

The Argentina skipper has scored four and assisted four in his last two matches for Inter Miami, and this Chile team at present are playing at an even lower level than most MLS clubs, so the Albiceleste number 10 could have a field day in Santiago.


Andrew graduated with a First Class Honours degree in Sports Journalism from UCFB in Manchester in 2022, and continues to live his dream of writing and reporting on sport. As well as football, Andrew closely follows Golf, Tennis and Athletics, and believes the Olympics is the world's greatest event.