Two European giants reconvene in Milan on Wednesday night. Our Inter Milan vs Bayern Munich prediction and Champions League betting tips consider whether Inter can hang on to their first-leg lead in this quarter-final tie.
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Inter Milan vs Bayern Munich prediction: Nerazzurri to make first-leg advantage count
Key stats
- Inter are unbeaten in 14 Champions League home matches – the longest current ongoing run in the competition.
- Bayern have only progressed in one of their previous eight Champions League knockout ties after losing the first leg.
- Inter have advanced in 21 of the last 23 Champions League knockout ties after winning the first leg.
Correct score prediction: Inter Milan 0-0 Bayern Munich
Inter are a side who are devastating in attack, but enjoy hanging on to what they have, and another defensive masterclass could be in store from Simone Inzaghi’s side at San Siro.
Bayern ran out of ideas in the first leg, and only got their goal through a lapse in concentration from the Inter backline, something which is unlikely to happen again.
Pre-game odds and win probability: Devilishly tight in the markets
- HOME: 13/8 (2.63) – 38.1%
- DRAW: 12/5 (3.40) – 29.4%
- AWAY: 6/4 (2.50) – 40.0%
*odds from Ladbrokes, subject to change
There is almost nothing to separate the sides in the odds but there is some good value in other markets, with both teams not to score priced at 5/4, and under 2.5 goals a very generous 11/10 in places.
Thanks to their first-leg win, Inter are big favourites to progress though, being priced at 3/10 to reach the semi-finals.
For more from the upcoming games in Europe, today’s football betting tips look at some of the best picks.
Most recent H2Hs: History favours the visitors
The first leg suggests this will be a lot closer than the group stage meetings in 2022 which both ended in 2-0 wins for the Bundesliga side, but Inter will hope history does not repeat itself, given they have lost all four home games against Bayern.
You don’t have to go too far back for happier memories for the Italians though. Inter memorably won the 2009/10 Champions League final 2-0 against Bayern, and they also progressed from a round-of-16 tie the following season.
UEFA Champions League 08/04/25

Bayern Munich

Inter Milan
UEFA Champions League 01/11/22

Bayern Munich

Inter Milan
UEFA Champions League 07/09/22

Inter Milan

Bayern Munich
Elite Club Friendlies 27/07/17

Bayern Munich

Inter Milan
Elite Club Friendlies 30/07/16

Inter Milan

Bayern Munich
Inter Milan preview: Inzaghi has all of his big-hitters available
Inzaghi was able to rotate at home to Cagliari at the weekend, leaving out the likes of Marcus Thuram and Alessandro Bastoni in the 3-1 league win, ahead of potentially reverting back to the same side from the first leg.
Mehdi Taremi is back from injury, and Kristjan Asllani is available after suspension, but Piotr Zielinski and Denzel Dumfries are out injured.
Predicted Lineup: Sommer (GK), Pavard, Acerbi, Bastoni, Darmian, Calhanoglu, Barella, Mkhitaryan, Dimarco, Martinez & Thuram
Italy Serie A 12/04/25 W Cagliari 1 Inter Milan 3 UEFA Champions League 08/04/25 W Bayern Munich 1 Inter Milan 2 Italy Serie A 05/04/25 D Parma 2 Inter Milan 2 Coppa Italia 02/04/25 D AC Milan 1 Inter Milan 1 Italy Serie A 30/03/25 W Udinese 1 Inter Milan 2
Bayern Munich preview: Kompany missing star man
Given the magnitude of their clash with Borussia Dortmund at the weekend, Vincent Kompant could not afford to rotate ahead of this clash, so it could be a similar side to the one lost in the first leg, and drew 2-2 in Der Klassiker.
The guests are missing goalkeeper Manuel Neuer and defenders Alphonso Davies and Dayot Upamecano to injury, while Jamal Musiala is the major absentee, meaning Thomas Muller and Raphael Guerreiro are battling to start in his place.
Predicted Lineup: Urbig (GK), Laimer, Dier, Kim, Stanisic, Goretzka, Kimmich, Olise, Guerreiro, Sane & Kane
Germany Bundesliga I 12/04/25 D Borussia Dortmund 2 Bayern Munich 2 UEFA Champions League 08/04/25 L Inter Milan 2 Bayern Munich 1 Germany Bundesliga I 04/04/25 W Augsburg 1 Bayern Munich 3 Germany Bundesliga I 29/03/25 W St Pauli 2 Bayern Munich 3 Germany Bundesliga I 15/03/25 D Union Berlin 1 Bayern Munich 1
Player to watch: Lautaro Martinez
After scoring in the first leg, Martinez became the first Inter player since Samuel Eto'o in 2010-11 to reach seven Champions League goals in a single campaign.

Another goal for the Inter skipper here will see him become the first Nerazzurri player in history to net in five consecutive Champions League matches.