Bayer Leverkusen vs TSG Hoffenheim prediction, odds & betting tips – 23/08/2025
Can Hoffenheim finally end their poor run against Leverkusen? Photo by IMAGO
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Bayer Leverkusen to win & Over 2.5 goals

Leverkusen have seen several key figures depart the club this summer, and the new campaign comes with a high degree of uncertainty. Still, we are backing the 2023 champions to emphatically get themselves underway on a winning note.

Bayer Leverkusen and TSG Hoffenheim will raise the curtain on their respective 2025/26 Bundesliga campaigns with a meeting at BayArena on Saturday afternoon.

Here at Football Whispers, we will be previewing the clash in this Bayer Leverkusen vs TSG Hoffenheim prediction article.

Bayer Leverkusen vs TSG Hoffenheim prediction: Winning start for Ten Hag

Key stats

  • Winning nine games on the trot, Hoffenheim have been in splendid form lately and are on a run of four straight matches without conceding.
  • Scoring first has contributed significantly to Hoffenheim's recent success, as they have broken the deadlock in six straight matches leading up to this weekend's outing.
  • Leverkusen are also no strangers to opening the scoring in matches, something they have done in all but one of their most recent five involvements.
  • The battle for supremacy at half-time this weekend is set to be intense, with the hosts going into the interval ahead in four of their last five matches, while the visitors have only failed to lead one of their last eight matches at the break.

Correct score prediction: Bayer Leverkusen 3-1 TSG Hoffenheim

Leverkusen have seen several key figures depart the club this summer, and the new campaign comes with a high degree of uncertainty.

Still, we are backing the 2023 champions to emphatically get themselves underway on a winning note.

Pre-game odds and win probability: Leverkusen well well-fancied to get the job done

  • HOME: 1/2 (1.50) – 66.7%
  • DRAW: 18/5 (4.60) – 21.7%
  • AWAY: 9/2 (5.50) – 18.2%

*Odds from Ladbrokes, subject to change

Leverkusen failed to win any of their final three league matches of the 2024/25 campaign, but have been given a 66.7% chance of ending that run this weekend.

Erik ten Hag's men made light work of Großaspach to secure safe passage into the next round of this season's DFB Pokal, thanks to strikes from Patrik Schick, Arthur, Christian Kofane and Alejandro Grimaldo.

Like their hosts, Hoffenheim also made light work of lower league opponents in their cup opener against Rostock, which ended in a comprehensive 4-0 triumph.

Max Moerstedt was the star of the show as he netted twice in the second half to fire Christian Ilzer's men to victory.

Going up against more illustrious opponents this weekend, Moerstedt have only been given an 18.2% chance of pulling off what would be a huge upset.

For more from the upcoming matches, today’s free football betting tips look at some of the best picks.

Most recent H2Hs: Leverkusen eyeing six wins in a row

Leverkusen picked up six points from a possible six across both of last season's meetings to take their winning run in this fixture to five games since a shock 3-0 defeat back in 2022.

The home side have won the aforementioned five games by a combined score of 15-6, highlighting their dominance.

Germany Bundesliga I 02/02/25

Bayer Leverkusen

Bayer Leverkusen

3
TSG Hoffenheim

TSG Hoffenheim

1

Germany Bundesliga I 14/09/24

TSG Hoffenheim

TSG Hoffenheim

1
Bayer Leverkusen

Bayer Leverkusen

4

Germany Bundesliga I 30/03/24

Bayer Leverkusen

Bayer Leverkusen

2
TSG Hoffenheim

TSG Hoffenheim

1

Germany Bundesliga I 04/11/23

TSG Hoffenheim

TSG Hoffenheim

2
Bayer Leverkusen

Bayer Leverkusen

3

Germany Bundesliga I 11/02/23

TSG Hoffenheim

TSG Hoffenheim

1
Bayer Leverkusen

Bayer Leverkusen

3

Bayer Leverkusen preview: Claudio Echeverri unlikely to make debut

Claudio Echeverri is Leverkusen's most recent arrival in what has been a busy summer, but the Manchester City loanee is not available for selection this weekend as he continues to nurse an ankle issue.

Martin Terrier is also a guaranteed absentee due to an Achilles' tendon injury, while Jonas Hofmann and Exequiel Palacios are doubts with muscle problems.

Predicted lineup: Flekken (GK), Quansah, Tapsoba, Hincapie, Arthur, Andrich, Garcia, Grimaldo, Tella, Maza & Schick

Germany Bundesliga I 11/05/25

L

Borussia Dortmund

Borussia Dortmund

4

Bayer Leverkusen

Bayer Leverkusen

2

Germany Bundesliga I 04/05/25

D

SC Freiburg

SC Freiburg

2

Bayer Leverkusen

Bayer Leverkusen

2

Germany Bundesliga I 26/04/25

W

Augsburg

Augsburg

0

Bayer Leverkusen

Bayer Leverkusen

2

Germany Bundesliga I 20/04/25

D

St Pauli

St Pauli

1

Bayer Leverkusen

Bayer Leverkusen

1

Germany Bundesliga I 12/04/25

D

Union Berlin

Union Berlin

0

Bayer Leverkusen

Bayer Leverkusen

0

TSG Hoffenheim preview: Adam Hlozek unavailable to face former employers

Adam Hlozek would have been keen to get one over his former side on Saturday, but an ankle injury will keep the striker from participating.

Valentin Gendrey is also out of contention with a broken leg and is joined on the visitors' treatment table by long-term absentee Ozan Kabak (knee).

Predicted lineup: Baumann (GK), Bernardo, Machida, Hranac, Coufal, Burger, Avdullahu, Toure, Kramaric, Lemperle & Asslani

Germany Bundesliga I 09/05/25

D

Wolfsburg

Wolfsburg

2

TSG Hoffenheim

TSG Hoffenheim

2

Germany Bundesliga I 03/05/25

D

Borussia M'gladbach

Borussia M'gladbach

4

TSG Hoffenheim

TSG Hoffenheim

4

Germany Bundesliga I 26/04/25

L

Borussia Dortmund

Borussia Dortmund

3

TSG Hoffenheim

TSG Hoffenheim

2

Germany Bundesliga I 19/04/25

L

SC Freiburg

SC Freiburg

3

TSG Hoffenheim

TSG Hoffenheim

2

Germany Bundesliga I 12/04/25

W

Mainz

Mainz

0

TSG Hoffenheim

TSG Hoffenheim

2

Player to watch – Patrik Schick

Netting 27 times across all competitions last time out, Schick recorded his highest-ever scoring season and was rewarded with a new contract until 2030.

The Czech Republic international has wasted no time opening his account for the new campaign and will head into Saturday's affair having scored six times in his last eight competitive matches for club and country.

Patrik Schick will be central to Leverkusen's plans this season – Photo by IMAGO

With Victor Boniface currently on his way out of Leverkusen, Die Werkself will need Schick in peak form as they aim to reclaim their league crown from Bayern Munich.

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Trading in blueprints for bylines, Marvellous is an engineering graduate who has found his true calling in sports writing. A dedicated Chelsea fan who also follows the NBA, he enjoys blending his love for football and basketball with thoughtful commentary and a relatable voice that keeps readers connected.