Bayer Leverkusen vs Sparta Prague prediction
Bayer Leverkusen are odds-on favourites to beat Sparta Prague. (Photo by Imago)
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Bayer Leverkusen to win-to-nil

Bayer Leverkusen have won each of their last three home games in the Champions League to nil.

Bayer Leverkusen take one Sparta Prague at the BayArena in what could be a one-sided Champions League fixture on Wednesday, 29 January. Read our Champions League predictions for the clash below.

Bayer Leverkusen vs Sparta Prague prediction: Visitors stand little chance

Key Stats

  • Bayer Leverkusen have won each of their last three home games in the Champions League to nil.
  • Sparta Prague have lost five matches in a row in the Champions League group stage.
  • Patrik Schick has scored eight goals in his last six appearances for Bayer Leverkusen.
  • Sparta shipped nine goals combined in their last two away assignments in the UCL group phase.

Correct score prediction: Bayer Leverkusen 4-0 Sparta Prague

Sparta Prague lost 5-0 to Man City and 4-2 to Feyenoord in their last two away games in the Champions Leagues, so expect the Czech outfit to struggle again when they travel to take on Bayer Leverkusen.

Pre-game odds and win probability: Leverkusen clear favourites

  • HOME: 1/8 (1.13) – 88.9%
  • DRAW: 17/2 (9.50) – 10.5%
  • AWAY: 16/1 (17.00) – 5.9%

*odds from Ladbrokes, subject to change

Bayer Leverkusen let a two-goal lead slip at RB Leipzig (2-2) at the weekend, though Die Werkself should find the going easier when they kick off as 1/8 favourites against Sparta Prague.

Sparta Prague have played just one competitive fixture since mid-December. They lost 1-0 at home to Inter Milan on that occasion and they have just a 5.9% chance of delivering a better result when they visit Leverkusen. Check out our football tips page for more of the best Champions League predictions.

Most recent H2Hs: First meeting since 2007

Bayer Leverkusen and Sparta Prague last met in the Europa League group stage back in 2007. Leverkusen eked out a 1-0 win on that occasion.

Bayer Leverkusen preview: Frimpong, Tella and Grimaldo could start

Amine Adli, Martin Terrier and Jeanuel Belocian are out of action for Bayer Leverkusen. Exequiel Palacios, Nathan Tella, Jeremie Frimpong, Victor Boniface and Alex Grimaldo could all return to the starting XI having been benched at the weekend.

Predicted lineup: Kovar (GK), Tah, Tapsoba, Hincapie, Frimpong, Palacios, Xhaka, Grimaldo, Wirtz, Tella, Schick

Germany Bundesliga I 11/05/25

L

Borussia Dortmund

Borussia Dortmund

4

Bayer Leverkusen

Bayer Leverkusen

2

Germany Bundesliga I 04/05/25

D

SC Freiburg

SC Freiburg

2

Bayer Leverkusen

Bayer Leverkusen

2

Germany Bundesliga I 26/04/25

W

Augsburg

Augsburg

0

Bayer Leverkusen

Bayer Leverkusen

2

Germany Bundesliga I 20/04/25

D

St Pauli

St Pauli

1

Bayer Leverkusen

Bayer Leverkusen

1

Germany Bundesliga I 12/04/25

D

Union Berlin

Union Berlin

0

Bayer Leverkusen

Bayer Leverkusen

0

Sparta Prague preview: Preciado could miss out again

Sparta Prague could still be without injured duo Angelo Preciado and Imanol Garcia this week. The visitors set up in a 3-5-2 formation against Inter Milan last time out and could use a similar shape when they visit Germany to take on Bayern Munich.

Predicted lineup: Vindahl (GK), Vitik, Panak, Sorensen, Wiesner, Sadilek, Kairinen, Laci, Rynes, Olatunji, Birmancevic

Czechia First League 10/05/25

L

Slavia Prague

Slavia Prague

2

Sparta Prague

Sparta Prague

1

Czechia First League 04/05/25

L

FK Jablonec

FK Jablonec

3

Sparta Prague

Sparta Prague

1

Czechia First League 27/04/25

L

Viktoria Plzen

Viktoria Plzen

2

Sparta Prague

Sparta Prague

0

Czechia Cup 23/04/25

W

Viktoria Plzen

Viktoria Plzen

0

Sparta Prague

Sparta Prague

1

Czechia First League 19/04/25

W

Pardubice

Pardubice

1

Sparta Prague

Sparta Prague

2

Player to watch – Patrik Schick

Wednesday’s fixture should be one of special significance for Bayer Leverkusen striker Patrick Schick, who is set to line up against his former club when he faces Sparta Prague.

Bayer Leverkusen vs Sparta Prague prediction
Patrik Schick will be determined to score against his old club. (Photo by Imago)

Schick will be keen to put on a show

Patrick Schick came through the Sparta Prague youth academy before leaving in 2016 and the 29-year-old will be determined to showcase his talents against his former club when Leverkusen meet the Czech outfit on Wednesday evening.

ucl betting odds

Simon Winter is a professional football tipster and sports journalist with over ten years in the industry. Best known for his time with Racing Post, Simon has also had work published by Freesupertips, Bloomberg Sports, bet365, Paddy Power, Colossus Bets, These Football Times and more. Simon covers the Bundesliga and Serie A for Football Whispers.