Tottenham Hotspur will turn their attention away from their Premier League relegation battle when they travel to the Wanda Metropolitano for their Champions League last-16 first leg against Atletico Madrid.
Despite the current threat of dropping into the Championship, the Europa League holders have had a good season in Europe and will look to travel back to North London still in contention for qualifying for the quarter-finals.
As for Diego Simeone's side, they will be looking for a fifth win in six in all competitions after making it to this stage by overcoming Club Brugge 7-4 across two legs in the playoff rounds.
Read on for our Atletico Madrid vs Tottenham Hotspur predictions and betting tips, and click here to find more betting tips for today.
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Atletico Madrid vs Tottenham Hotspur key stats
- The pair meet for the first time in more than 60 years, with Spurs winning the previous encounter 5-1 in the 1963 European Cup Winners' Cup final in Rotterdam.
- Diego Simeone's side reach this stage of the Champions League for the 11th time in 13 seasons, despite finishing 14th in the league phase.
- The Spanish side have kept 13 clean sheets in their last 18 knockout games in their own stadium.
Atletico Madrid vs Tottenham Hotspur preview: A pivotal first leg at Wanda Metropolitano
| Atletico Madrid | vs | Tottenham Hotspur |
|---|---|---|
| 3rd (LaLiga) | Position | 16th (Premier League) |
| 54 | Points | 29 |
| 46 | Goals For | 39 |
| 25 | Goals Against | 46 |
| 11 | Clean Sheets | 6 |
| 2nd | Home Rank | 19th |
| 6th | Away Rank | 9th |
These two sides head into this Champions League tie in contrasting form in their respective domestic leagues, with Atletico Madrid picking up 25 more points than Tottenham Hotspur.
As well as the significant difference in points picked up, Tuesday night's hosts have scored more goals, conceded fewer and are a much better side at home.
Spurs have opened the scoring in their last five Champions League matches and kept five clean sheets in the last six.
The fact Tottenham placed 10 places above Atletico Madrid in the league phase is remarkable but they will still know they will be up against it if they are to claim their first win under new manager Igor Tudor.
We are coming to the business end of the season and Tottenham will be eager to maintain Premier League status for next season over a deep run into the Champions League, but all the stats for this year's competition would suggest they are the team to beat.
Yet to win in the Premier League in 2026, they have won two from two in Europe's greatest competition after overcoming Borussia Dortmund and Eintracht Frankfurt.
However, their last Champions League game was under different management and back in January.
Atletico Madrid's dramatic 7-4 win was their second crazy cup tie after reaching the Copa del Rey final 4-3 on aggregate, despite losing the second leg 3-0.
Tottenham have also lost all four two-legged ties against Spanish opposition; this is their first since going down 5-0 on aggregate to Real Madrid in the 2010/11 quarter finals.
Simeone's team have had a more relaxed time of it in the league with three straight wins to their name, but the title remains out of touch for this season.
Atleti could still end the campaign with two pieces of silverware so will be keen to head to London with an advantage, they will be hoping their strong defensive unit can come strong once again.
Atletico Madrid vs. Tottenham Hotspur form guide & betting tips
| Atletico Madrid | vs | Spurs |
|---|---|---|
| W-W-W-L-W | Form | L-L-L-L-L |
| 9 | Points | 0 |
| 6th | Form Table | 20th |
| 12 | Goals For | 4 |
| 8 | Goals Against | 13 |
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Whispers predicts: Atletico Madrid 3-1 Tottenham Hotspur
Despite good form in the Champions League, the pair could barely be further apart in recent times. Unsurprisingly, the bookmakers have the hosts as clear favourites.
A home win is placed at 8/15, while an away win is seen as way more unlikely at 5/1.
We see four goals being scored and the bookmakers have odds of 4/6 for there to be over 2.5.
Both teams to score and a home win is priced at 11/5, while both teams to score and Spurs to win is at 10/1.
> BTTS - No at 1/1 | Likelihood: Probable
> Over 2.5 goals at 4/6| Likelihood: Probable
> Double Chance - Draw or Spurs at 11/8 | Likelihood: Possible
> Home & BTTS - No at 13/8 | Likelihood: Probable
> Correct score: 3-1 at 11/1| Likelihood: Outsider