The San Siro will witness the top-of-the-table clash between AC Milan and AS Roma on Sunday in game week 10 of the Serie A.
The Rossoneri enter this game second on the league table, having been unbeaten in their last five games. However, despite their form, they failed to get a win last weekend, as they were held to a 1-1 draw by Atalanta.
On the other hand, the Giallorossi have not had a good run of form in their last five games, but sit second above their opponent. However, they have won back-to-back games in the league, with their recent win being a 2-1 victory over Parma.
Read our AC Milan vs Roma predictions and preview to find out, but remember to also check our other Serie A predictions.
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AC Milan vs Roma prediction: Home team to win by a narrow margin
Key statistics
- At least four goals have been scored in three of their last five meetings.
- AC Milan have won two of their last five home games against Roma.
- Their last five clashes have ended in BTTS.
Correct score prediction: AC Milan 3-1 Roma
Given the superb form of both teams, coupled with their rivalry, we expect the game to be difficult for Roma, but we predict that AC Milan will win the game 3-1 at the San Siro.
This fixture often results in narrow margins and while both teams have a strong attack, we believe the home advantage and form posed by the Rossoneri will give them an edge. We tip the home team to use the advantage they have and seal a win over Roma.
Pre-match odds and win probability: AC Milan made slight favourites
- Home: 21/20 (2.05) – 48.8%
- Draw: 9/4 (3.25) – 30.8%
- Away: 14/5 (3.80) – 26.3%
Odds provided by Ladbrokes. Subject to change.
The home side head into the match as slight favourites at 2.05, giving them a 48.8% chance of victory according to bookmakers.
The draw is set at 3.25 with a 30.8% probability, while the away side are priced at 3.80, suggesting a 26.3% chance of success. Overall, the odds indicate a closely balanced game, with the hosts holding a slight edge.
Most recent head-to-head: Evenly matched rivalry
Looking at the last five Serie A head-to-head fixtures between AC Milan and Roma, it shows a very tight encounter, with AC Milan securing two home victories and Roma claiming one win, alongside two draws.
These matches frequently feature goals, with three of the last six encounters finishing with lots of goals. The last home meeting ended in a 3-1 win for AC Milan, but the game was a Coppa Italia clash.
Italy Serie A 18/05/25
Roma
AC Milan
Coppa Italia 05/02/25
AC Milan
Roma
Italy Serie A 29/12/24
AC Milan
Roma
Elite Club Friendlies 31/05/24
AC Milan
Roma
UEFA Europa League 18/04/24
Roma
AC Milan
After reviewing our key AC Milan vs Roma predictions, be sure to visit our website for the remaining football betting tips today.
AC Milan preview: Several players to miss clash
Several key players remain unavailable through injury for Massimiliano Allegri’s team. Pervis Estupinan is sidelined with a thigh injury and is expected to return in November.
Adrien Rabiot also continues his recovery from a calf issue with a similar return timeline. Ardon Jashari is ruled out until December due to injury, and Christian Pulisic is also out with a hamstring problem.
Predicted lineup: Maignan (GK), Tomori, Gabbia, Pavlovic, Saelemaekers, Fofana, Ricci, Modric, Bartesaghi, Gimenez & Leao
Last five fixtures
- 28.10.25 – Atalanta 1 – 1 AC Milan
- 24.10.25 – AC Milan 2 – 2 Pisa
- 19.10.25 – AC Milan 2 – 1 Fiorentina
- 05.10.25 – Juventus 0 – 0 AC Milan
- 28.09.25 – AC Milan 2 – 1 Napoli
Roma preview: Key players out due to injury and suspension
On the other hand, Roma will be without Edoardo Bove, who remains sidelined due to ongoing heart issues, while Evan Ferguson is recovering from a thigh injury and is expected back by November. Angelino is also unavailable after being struck by a virus, with a similar return timeline later in the month.
Predicted lineup: Svilar (GK), Celik, Mancini, N'Dicka, Hermoso, Cristante, Kone, Wesley, Soule, Dybala & Bailey
Last five fixtures
- 29.10.25 – AS Roma 2 – 1 Parma
- 26.10.25 – Sassuolo 0 – 1 AS Roma
- 23.10.25 – AS Roma 1 – 2 Plzen
- 18.10.25 – AS Roma 0 – 1 Inter
- 05.10.25 – Fiorentina 1 – 2 AS Roma
Player to watch: Rafael Leao
AC Milan star Rafael Leao will have to continue his scoring form in a bid to help his team continue their impressive form.
The winger has scored three goals in his last two games, with the most recent goal coming in their 2-2 draw against Pisa. Roma will need to find a way to stop the Portuguese forward if they need to avoid a defeat against the home team.