AC Milan vs Napoli prediction, odds & betting tips – 28/09/2025
Milan are favourites with bookmakers - Photo by Imago
🔥 Our Hot tip

Under 2.5 total goals

Milan have kept four successive clean sheets.

An exciting battle between two of Serie A's current top three will commence at San Siro on Sunday night as AC Milan play host to Napoli. The Rossoneri are in great form, and so will fancy themselves to get a positive result against the reigning Scudetto holders.

Meanwhile, Napoli have enjoyed a perfect start to their title defence, winning all of their opening four league games so far this season. Nonetheless, it will be interesting to see how they cope at San Siro against an in-form Milan.

AC Milan vs Napoli prediction: Visitors to be denied another victory?

Key stats

  • Milan have won four games in a row in total in all competitions.
  • Napoli have lost just once in nine matches across all competitions.
  • Milan have won just once in five H2Hs.

Correct score prediction: AC Milan 1-1 Napoli

Given that both teams are in such great form, they could end up cancelling each other out. We are backing Milan to end Napoli's 100% start to the league season.

Pre-game odds and win probability: Milan favourites with bookmakers

  • HOME: 11/8 (2.38) – 42.1%
  • DRAW: 11/5 (3.20) – 31.3%
  • AWAY: 2/1 (3.00) – 33.3%

*odds from Ladbrokes, subject to change

As shown by the implied probabilities, Milan are actually the favourites with bookmakers to claim all three points on home soil. Interestingly, a draw and a Napoli victory away from home are separated by just 2%.

Also, feel free to check out our dedicated Football Betting Tips Today page, as well as our Serie A predictions & betting tips page.

Most recent H2Hs: Napoli hold upper hand

As mentioned before, Milan have won just one of the previous five meetings in total in all competitions. Napoli won both league fixtures last season as well, but the Rossoneri are in top form and so will not be easy to bet.

Italy Serie A 30/03/25

Napoli

Napoli

2
AC Milan

AC Milan

1

Italy Serie A 29/10/24

AC Milan

AC Milan

0
Napoli

Napoli

2

Italy Serie A 11/02/24

AC Milan

AC Milan

1
Napoli

Napoli

0

Italy Serie A 29/10/23

Napoli

Napoli

2
AC Milan

AC Milan

2

UEFA Champions League 18/04/23

Napoli

Napoli

1
AC Milan

AC Milan

1

AC Milan preview: Leao to return to squad?

Rafael Leao could return to the squad for the first time this season after injury, but may only be fit enough for the bench. Ardon Jashari is still sidelined for Milan.

Predicted lineup: Maignan (GK); Tomori, Gabbia, Pavlovic; Saelemaekers, Fofana, Modric, Rabiot, Estupinan; Pulisic & Gimenez

Last five results:

  • AC Milan 3-0 Lecce
  • Udinese 0-3 AC Milan
  • AC Milan 1-0 Bologna
  • Lecce 0-2 AC Milan
  • AC Milan 1-2 Cremonese

Napoli preview: Buongiorno injury blow

Alessandro Buongiorno will be missing for Napoli after injuring himself in their previous match. Romelu Lukaku is a long-term absentee.

Predicted lineup: Meret (GK); Di Lorenzo, Beukema, Jesus, Spinazzola; Lobotka; Politano, Anguissa, De Bruyne, McTominay & Hojlund

Last five results:

  • Napoli 3-2 Pisa
  • Manchester City 2-0 Napoli
  • Fiorentina 1-3 Napoli
  • Napoli 1-0 Cagliari
  • Sassuolo 0-2 Napoli

Player to watch: Christian Pulisic

AC Milan vs Lecce prediction

Christian Pulisic has started the season brilliantly for Milan, with five goals and an assist in all competitions so far this season. Three of those goal contributions came in the Rossoneri's last league outing, a 3-0 win away at Udinese, and so Napoli will be very aware of the quality that the USA international possesses, and just how he can hurt them on the pitch.


Adam is a lead writer on Football Whispers. He is a big Arsenal fan, and also follows his local club Wealdstone, made famous by The Wealdstone Raider, who he has interviewed. Adam also follows darts, boxing, cricket and tennis, among many other sports.