AC Milan face a difficult opponent in Lazio on Saturday when they welcome them to the San Siro for the 13th round of the Serie A season. Both teams are fighting for a top-four spot on the table, with the hosts looking to maintain second place and keep the pressure on league leaders Roma.
The Rossoneri come into this fixture looking confident after painting Milan red and black with a massive 1-0 victory over city rivals Inter last weekend. That result extended their unbeaten run in their last five games and confirmed their title credentials.
On the other hand, the Biancocelesti have also found some form, bouncing back from a defeat to Inter earlier in the month with a solid 2-0 home win against Lecce. Lazio currently sit in ninth place, having won three, drawn two and lost one of their last five games.
Read our AC Milan vs Lazio predictions and preview to find out, but remember to also check our other Serie A predictions.
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AC Milan vs Lazio prediction: Home team to claim victory
Key statistics
- First-half draws have been played in three of their last five meetings.
- AC Milan are unbeaten in their last five games in all competitions.
- Their last two encounters ended with both teams scoring.
Correct score prediction: AC Milan 2-1 Lazio
Looking at the form of both teams, we expect a tight game, but we believe the home side to edge this encounter, with a home advantage playing a role. AC Milan have turned the San Siro into a fortress this season and their recent defensive resilience in the derby suggests they can handle Lazio's attacking threat.
Lazio have struggled in big away games recently, losing 2-0 to Inter at this same venue earlier in November. However, they can still cause a big upset in games like this. We believe the Rossoneri will claim a narrow 2-1 victory in this clash.
Pre-match odds and win probability: AC Milan are the favourites
- Home: 8/13 (1.62) – 61.9%
- Draw: 11/4 (3.75) – 26.7%
- Away: 9/2 (5.50) – 18.2%
*Odds provided by Ladbrokes. Subject to change.*
AC Milan enter this fixture as the favourites, with the home team given 1.62 odds, giving them a 61.9% chance of victory. The draw is offered at 3.75 (26.7%), while an away win for Lazio is priced at 5.50, translating to an 18.2% probability of an upset.
Most recent head-to-head: AC Milan dominate past meetings
The recent history between these two Italian giants suggests the games have been competitive, but AC Milan have had more wins in their last five encounters. The home team have won three times, while Lazio have claimed one victory, with one match ending in a draw. Interestingly, Lazio won the last encounter at the San Siro 1-2 back in March 2025, a result that Milan will be desperate to avenge this time around.
Italy Serie A 02/03/25
AC Milan
Lazio
Italy Serie A 31/08/24
Lazio
AC Milan
Italy Serie A 01/03/24
Lazio
AC Milan
Italy Serie A 30/09/23
AC Milan
Lazio
Italy Serie A 06/05/23
AC Milan
Lazio
After reviewing our key AC Milan vs Lazio predictions, be sure to visit our website for the remaining football betting tips today.
AC Milan preview: No new injury concerns
AC Milan have no new injury concerns, aside from the player who has been sidelined for some time. Santiago Gimenez remains out with an ankle injury, with a return anticipated in early December, while Zachary Athekame is also unavailable as he recovers from a muscle problem, aiming for a similar comeback timeframe.
Predicted lineup: Maignan (GK), Saelemaekers, Tomori, Gabbia, Pavlovic, Fofana, Rabiot, Pulisic, Modric, Bartesaghi & Leao
Last five fixtures
- 23.11.25 – Inter 0–1 AC Milan
- 08.11.25 – Parma 2–2 AC Milan
- 02.11.25 – AC Milan 1–0 AS Roma
- 28.10.25 – Atalanta 1–1 AC Milan
- 24.10.25 – AC Milan 2–2 Pisa
Lazio preview: Fitness concerns for the visitors
Lazio are struggling to get some of their players fit ahead of this encounter. Samuel Gigot is doubtful with a muscle injury, while Nicolo Rovella is also uncertain to play due to a groin problem.
Matteo Cancellieri and Valentin Castellanos are both sidelined with muscle injuries, with returns expected in early December. Danilo Cataldi remains unavailable as he continues his recovery from a calf injury.
Predicted lineup: Provedel (GK), Marusic, Patric, Romagnoli, Pellegrini, Vecino, Guendouzi, Basic, Isaksen, Zaccagni & Dia
Last five fixtures
- 23.11.25 – Lazio 2–0 Lecce
- 09.11.25 – Inter 2–0 Lazio
- 03.11.25 – Lazio 2–0 Cagliari
- 30.10.25 – Pisa 0–0 Lazio
- 26.10.25 – Lazio 1–0 Juventus
Player to watch: Christian Pulisic
Christian Pulisic will play a key role in this game for AC Milan, as he has done in other games this season. The USA attacker has proven himself to be consistent and a goal threat in front of the goal in this campaign.
Pulisic has scored five goals and provided one assist in Serie A this season, including the winning goal against Inter Milan last weekend. His sharp movement and finishing make him a huge threat in this game.