This season's fifth instalment of the Derby della Madonnina takes place in the second leg of the semi-finals of the Coppa Italia on Wednesday. Our Inter Milan vs AC Milan prediction considers who could take their place in the final.
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Inter Milan vs AC Milan prediction: Nerazzurri to wrestle back Milanese supremacy
Key stats
- Our Inter Milan vs AC Milan betting tips take into account that the Nerazzurri have not lost at San Siro in 21 matches, dating back to mid-September.
- Inter have won the last three cup ties between the sides, in this competition in 2021 and 2022, as well as in the Champions League in 2023.
- Milan have won the Coppa Italia on five occasions, but their last success in the competition came all the way back in 2003.
- Inter have nine Coppa titles to their name, going back-to-back in 2022 and 2023.
Correct score prediction: Inter Milan 1-0 AC Milan
Inter may have stuttered against a tricky Bologna side at the weekend, but they are still favourites to complete a domestic double at the very least, and will enter the second leg as favourites.
Milan were also beaten at the weekend, but lost here at San Siro, and manager Sergio Conceicao remains under huge pressure after an underwhelming run of form.
Pre-game odds and win probability: Inter the clear favourites
- HOME: 10/11 (1.91) – 52.4%
- DRAW: 5/2 (3.50) – 28.6%
- AWAY: 27/10 (3.70) – 27.0%
*odds from Ladbrokes, subject to change
The designated home side are the favourites according to the bookies, with an implied probability of 52.4% that they win this match, and ultimately take their place in the final.
Taking into account all possibilities such as extra time and penalties, Inter are priced as short as 1/2 to qualify for the final, which is no surprise given their 21-game unbeaten home run.
For more from the upcoming matches in Europe, today’s free football betting tips look at some of the best picks.
Most recent H2Hs: Milan have the recent upper hand
Milan may be languishing down in ninth in the Serie A table, while Inter are chasing the treble, but the Rossoneri have not lost any of the four derbies played this season.
That comes as a huge surprise considering Inter had won six in a row before this campaign, and even won the title by beating Milan last year, but it should not be long before Simone Inzaghi's men get back to winning ways in this fixture.
Coppa Italia 02/04/25

AC Milan

Inter Milan
Italy Serie A 02/02/25

AC Milan

Inter Milan
Italy Super Cup 06/01/25

Inter Milan

AC Milan
Italy Serie A 22/09/24

Inter Milan

AC Milan
Italy Serie A 22/04/24

AC Milan

Inter Milan
Inter Milan preview: Thuram leaves a big hole in attack
Inter will have to cope without the injured Marcus Thuram, who picked up an issue during their win over Bayern Munich last week, so one of Joaquin Correa or Marko Arnautovic is set to lead the line with skipper Lautaro Martinez.
First-team options Denzel Dumfries and Piotr Zielinski are also out for the Nerazzurri, who should still go full strength, despite the Champions League semi-final with Barcelona being on the horizon.
Predicted Lineup: Sommer (GK), Pavard, Acerbi, Bastoni, Darmian, Barella, Calhanoglu, Mkhitaryan, Dimarco, Correa & Martinez
Italy Serie A 11/05/25 W Torino 0 Inter Milan 2 UEFA Champions League 06/05/25 W Barcelona 3 Inter Milan 4 Italy Serie A 03/05/25 W Verona 0 Inter Milan 1 UEFA Champions League 30/04/25 D Barcelona 3 Inter Milan 3 Italy Serie A 27/04/25 L Roma 1 Inter Milan 0
AC Milan preview: Depleted at right-back
Milan will be without one-half of their English contingent, as Kyle Walker and Ruben Loftus-Cheek are both sidelined after undergoing surgery recently, but Tammy Abraham could get the nod up front, while Fikayo Tomori is a nailed-on starter at the back.
Emerson Royal is the other injury absentee, leaving Milan short at right-back, with young Alejandro Jimenez expected to start again in that position.
Predicted Lineup: Maignan (GK), Tomori, Gabbia, Pavlovic, Jimenez, Fofana, Reijnders, Hernandez, Pulisic, Abraham & Leao
Italy Serie A 09/05/25 W Bologna 1 AC Milan 3 Italy Serie A 05/05/25 W Genoa 1 AC Milan 2 Italy Serie A 27/04/25 W Venezia 0 AC Milan 2 Coppa Italia 23/04/25 W Inter Milan 0 AC Milan 3 Italy Serie A 20/04/25 L Atalanta 1 AC Milan 0
Player to watch: Lautaro Martinez
The Inter captain has scored nine goals in this fixture, comfortably the most of any active player, and he enter the second leg in excellent form.

Martinez missed the first leg with injury, but on his return, he played a huge role in their two-legged success over Bayern Munich scoring in both legs, and he could well have a similar impact here.