San Diego vs Seattle Sounders prediction, odds & betting tips – 04/06/2025

San Diego FC
06/04/25 - 03:30

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Seattle Sounders

San Diego FC - Seattle Sounders

USA MLS - Snapdragon Stadium

The first official San Diego vs Seattle Sounders head-to-head will be played on the 6th of April at Snapdragon Stadium. We are more than excited about the upcoming Major League Soccer clash, as we are sure this will be one of the more interesting ones this week. Stay tuned for the inside scoop on our professional San Diego vs Seattle Sounders betting tips.

Make sure to check out the rest of our professional MLS Predictions this week.

San Diego vs Seattle Sounders prediction: Easy San Diego win expected

Our predictions

  • Hot tip: BTTS – Yes
  • Correct score – 3-1
  • Over 2.5 goals

Key Stats

  • Hot tip reasoning: San Diego recorded goals galore in four MLS games on the spin.
  • We saw over 2.5 goals in three of San Diego’s last four Major League Soccer games.
  • San Diego’s six Major League Soccer matches so far include three victories, two draws, and only one loss.
  • Seattle Sounders won only one of their MLS matches thus far.

Correct score prediction: San Diego 3-1 Seattle Sounders

Seeing as coach Mikey Varas has 1st place within arms’ reach, we believe our key San Diego vs Seattle Sounders predictions will succeed. The home team needs only two more points to advance to the top of the Western Conference’s table.

Pre-game odds and win probability: Bookies go with Varas’ side

  • HOME: +127 – 42.5%
  • DRAW: +265 – 27.0%
  • AWAY: +220 – 30.5%

*These San Diego vs Seattle Sounders odds are subject to change

BTTS – Yes at Snapdragon Stadium is what we will likely see this week, as the odds behind our top San Diego vs Seattle Sounders prediction are valued at -135. This translates to a 57.45% chance of success.

In the meantime, you should know that San Diego are the bookmakers’ expected winners. Coach Varas’ players keep a 42.5% win probability before the start of the game, which is indeed a convincing number.

Last five H2Hs: History in the making

The following graphics will supply you with much-needed knowledge regarding the key San Diego vs Seattle Sounders statistics.

San Diego team news and form: Injury headaches for Varas

Star striker Marcus Ingvarsten is injured and will miss the match against Seattle Sounders. The same goes for up-and-coming midfielder Manu Duah. However, we are sure that the manager will find the right men to get the job done.

Predicted lineup: dos Santos (GK), Loffelsend, McVey, McNair, Negri, De La Torre, Tsverkov, Godoy, Dreyer, Valakari & Lozano

USA MLS 13/04/25

L

Colorado Rapids

Colorado Rapids

3

San Diego FC

San Diego FC

2

USA MLS 06/04/25

W

Seattle Sounders

Seattle Sounders

0

San Diego FC

San Diego FC

3

USA MLS 30/03/25

W

Los Angeles FC

Los Angeles FC

2

San Diego FC

San Diego FC

3

USA MLS 23/03/25

L

Austin FC

Austin FC

2

San Diego FC

San Diego FC

1

USA MLS 16/03/25

D

Columbus Crew

Columbus Crew

1

San Diego FC

San Diego FC

1

Seattle Sounders team news and form: Winless Seattle hit new low

Coach Brian Schmetzer’s players haven’t won a game in quite some time now. They failed in the last four official games in all competitions. Even lost the CONCACAF Champions League versus Liga MX’s Cruz Azul.

Predicted lineup: Frei (GK), Tolo, Ragen, Gomez, A. Roldan Vargas, Paulo, Rothrock, Rusnak, Ferreira & Roldan

USA MLS 13/04/25

W

FC Dallas

FC Dallas

0

Seattle Sounders

Seattle Sounders

1

USA MLS 06/04/25

L

San Diego FC

San Diego FC

3

Seattle Sounders

Seattle Sounders

0

USA MLS 30/03/25

D

San Jose Earthquakes

San Jose Earthquakes

1

Seattle Sounders

Seattle Sounders

1

USA MLS 23/03/25

D

Houston Dynamo

Houston Dynamo

0

Seattle Sounders

Seattle Sounders

0

USA MLS 16/03/25

L

St. Louis City SC

St. Louis City SC

1

Seattle Sounders

Seattle Sounders

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Player to watch: Hirving Lozano

Mexican superstar Hirving Lozano was injured and skipped a few games for coach Varas’ team, but he is all better now and is expected to be among the starters for his new club. Since the start of the 2025 Major League Soccer campaign, the former PSV star has taken part in only one goal. However, we still have confidence in his abilities to prove our professional San Diego vs Seattle Sounders predictions correct.

San Diego vs Seattle Sounders Prediction 2
Photo by IMAGO

Second player to watch: Onni Valakari

Valakari, on the other hand, bagged two goals for coach Varas. Moreover, he is also the key creator on the team, with three assists under his belt.


Zack is a longtime football fan, writer, and bettor. He also has experience playing and coaching the game of football at a local level. His interest in the MLS, Liga MX and the Canadian Premier League adds a new dimension to the content we have at FootballWhispers.