The U.S. Men’s National Team is going up against Panama in an international friendly on the 13th of October. The game itself will be held at Q2 Stadium, but will Austin’s shrine come to the US’ aid? Find out the answer to this question in the following USA vs Panama betting tips. We have some exclusive knowledge to share with you this week.
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USA vs Panama prediction: A stroke of genius by Mauricio Pochettino’s players
Key Stats
- We saw over 2.5 goals in six of the last eight USA vs Panama head-to-heads.
- The last 10 games between the two countries resulted in five victories for the USA, three for Panama, and two 1-1 ties.
- Two of USA’s last four matches in all competitions saw over 2.5 goals.
Correct score prediction: USA 3-1 Panama
Historically speaking, Panama haven’t performed that poorly against the USMNT. That’s why we believe the visitors will eventually score a consolation goal at Q2 Stadium. Surely, our USA vs Panama prediction will succeed, as there’s a sheer class difference between the two teams for all to see.
Pre-game odds and win probability: Panama not capable of a surprise
- HOME: -330 – 75.2%
- DRAW: +400 – 18.8%
- AWAY: +1200 – 6.0%
*These USA vs Panama odds are subject to change
With odds valued at -330, Coach Pochettino’s players are considered by the experts as the expected winners at Q2 Stadium, with a 75.2% win probability behind them.
We checked the odds and saw that over 2.5 goals priced at -122 gives our key USA vs Panama prediction a massive 54.95% success chance.
Last five H2Hs: Advantage Panama
Surprisingly enough, it’s Panama who have the head-to-head advantage.
Copa America 27/06/24

Panama

USA
CONCACAF Gold Cup 13/07/23

USA

Panama
North & Central America - World Cup Qualifying 28/03/22

USA

Panama
Central America - World Cup Qualifying 10/10/21

Panama

USA
International Match 16/11/20

USA

Panama
USA team news and form: Pochettino to rotate squad
The bad news in front of the Argentine manager is that he won’t be able to count on Juventus star Timothy Weah. The 24-year-old midfielder sustained an ankle sprain and won’t be able to partake for the USMNT in the match against Panama.
Predicted lineup: Turner (GK), Richards, McKenzie, Hansen, Fossey, Musah, Morris, Pepi, Aaronson, Wright & Pulisic
CONCACAF Nations League 23/03/25
L

Canada
2

USA
1
CONCACAF Nations League 20/03/25
L

Panama
1

USA
0
International Match 23/01/25
W

Costa Rica
0

USA
3
International Match 18/01/25
W

Venezuela
1

USA
3
CONCACAF Nations League 19/11/24
W

Jamaica
2

USA
4
Panama team news and form: Panama are knocked down
Panama’s last match was a devastating 5-0 loss versus almighty Colombia. The game on the 7th of July shouldn’t have resulted in such a brutal defeat, as Panama didn’t play that poorly, with 48.0% ball possession and twice as many shots at target.
Predicted lineup: Mosquera (GK), Cordoba, Davis, Miller, Farina, Murillo, Blackman, Martinez, Barcenas, Welch & Fajardo
CONCACAF Nations League 24/03/25
L

Mexico
2

Panama
1
CONCACAF Nations League 20/03/25
W

USA
0

Panama
1
International Match 08/02/25
L

Chile
6

Panama
1
Club Friendly List 25/01/25
L

Universitario de Deportes
2

Panama
1
CONCACAF Nations League 19/11/24
D

Costa Rica
2

Panama
2
Player to watch: Christian Pulisic
Pochettino owes Captain America a debt of gratitude for his 69th-minute opener in the international friendly against New Zealand on the 11th of September. Pulisic is undoubtedly USMNT’s leader and we expect to see him among the starters in this important test for Pochettino.

Second player to watch: Jose Fajardo
Fajardo is the second player to watch in our key USA vs Panama prediction. He scored two goals for Panama during the World Cup Qualifiers and we are sure he will like to continue impressing his manager in order to cement his place among the starters for his country.