49ers vs Eagles prediction, odds and best bets 01/29/2023

The No. 2 seed San Francisco 49ers take on the No. 1 seed Philadelphia Eagles in a great matchup of this year’s NFC Championship Game. Let’s take a better look at this 49ers vs Eagles prediction with odds and analysis.

49ers vs Eagles prediction: top picks for Sunday

We have three of our favorite picks for this elite NFC matchup to determine the first Super Bowl participant. The 49ers vs Eagles odds have the Eagles as a 2.5-point home favorite with a total of 46.5 points.

Eagles -2.5 @ -110

Our best 49ers vs Eagles prediction is trusting the No. 1 seed to deliver at home against the rookie quarterback, Brock Purdy. No rookie has ever started a Super Bowl and they are 0-4 in these Conference Championship Games since 1999 with all throwing at least one costly interception.

The 49ers are 0-4 this year when they turn the ball over multiple times and 15-0 when they do not, so it is on the home defense to force the rookie into mistakes. He makes a few dangerous throws every week, but so far in the playoffs, no one has made him pay.

The Eagles had 70 sacks this year and have held all but two quarterbacks under 225 passing yards in 18 games. They are the No. 1 pass defense and they have an MVP finalist at quarterback in Jalen Hurts, who has rushed for 14 touchdowns including the playoffs.

The Eagles have lost one game all season with Hurts, and that involves four turnovers by the Eagles. The 49ers have the No. 1 defense, but they can be had through the air by a good passing offense. The Eagles are balanced and can run and pass and Hurts himself can run if necessary. He rushed for over 80 yards and a touchdown the last time he faced San Francisco.

The 49ers have had a remarkable 12-game winning streak, but the Eagles are the only team left this weekend with no glaring flaw. Trust the Eagles to take advantage of Purdy’s inexperience and win this game.

Over 46.5 Points @ -110

These teams played games that went under 46.5 points last week, but both have great offensive lines, great skill players, and their quarterbacks can run. They have a lot of talent and unique schemes with their coaching staffs, and they are unfamiliar opponents with their last meeting coming in Week 2 of the 2021 season.

Even in that 17-11 game, both teams left many points on the field as the Eagles had a 91-yard pass completion to Quez Watkins that somehow led to zero points.

The Eagles are much better now with A.J. Brown at wide receiver, and the 49ers have been almost flawless since trading for Christian McCaffrey. Do not forget the likes of George Kittle, Brandon Aiyuk, Deebo Samuel, DeVonta Smith, Miles Sanders, and Dallas Goedert.

These teams are loaded with playmakers and it should be more offensive this week than the 19-12 and 38-7 games they played last week. Take the over to hit as turnovers can lead to short fields and drive up points.

Jalen Hurts Anytime TD Scorer @ +125

Our final 49ers vs Eagles prediction is a player prop with Jalen Hurts scoring what would be his 15th rushing touchdown this season. He has been great at called runs near the end zone this year, and he did it again last week against the Giants with a 5-yard run where he was barely touched as he showed off his speed.

The 49ers have shut down most running backs this year, but Hurts gives the Eagles an edge behind that great offensive line to efficiently score touchdowns in the red zone. He is the safest bet for a touchdown scorer this week.

How to watch the 49ers vs Eagles 2022 NFC championship game?

• The game between the San Francisco 49ers and Philadelphia Eagles will be played on 01/29/2023 at 03:00 PM ET.
• The game will be broadcast live on FOX.

Top questions about the 49ers vs Eagles prediction in the Conference championship game

Here are some of the top questions and answers about the 49ers vs Eagles game this Sunday afternoon.

Where is the game being played?

The game is being played at Lincoln Financial Field in Philadelphia, Pennsylvania.

Is Christian McCaffrey (calf) playing?

Yes, running back Christian McCaffrey did not practice on Wednesday or Thursday for a calf injury sustained in last week’s game, but he insists there is zero chance he will miss this game for the 49ers.

What is a good betting trend for the Eagles' odds to win the game?

In home games under Nick Sirianni since 2021, the Eagles are 9-3-1 ATS as a favorite, the best record in the league in that time.

What is San Francisco’s spread record?

In 2022, the 49ers are 13-6 ATS, the fourth-best record in the league.