Manchester United have had a nearly perfect start to the Premier League season.
The Red Devils have won four and drawn the other one of their five Premier League games, and will hope to continue their unbeaten start against Southampton.
The corresponding match last season finished 0-0 as United focused on the Europa League final.
The other two meetings between the two sides saw United win 2-0 at Old Trafford and a 3-2 EFL Cup final win for José Mourinho’s team.
Kick off at St Mary’s is at 3pm and the game isn’t being shown live on TV.
Use our predicted lineups feature at the top of the page to pick and share the side you would pick if you were Mourinho on Saturday.
Our unique algorithm has predicted the starting XI it believes is most likely to start, but you can also give it a go yourself.
Just click ‘create your own’ and pick the XI players you would choose, and you can also see their stats per 90 minutes once you’ve picked them.
When you’re happy with your team, press confirm and you’ll be able to share it wth your friends via social media.