Yet with APOEL a minnow in the group, it may be the best chance the Argentine gets to get any European action.
Mousa Dembélé is also doubtful due to a recurring ankle issue.
Use our predicted lineups feature at the top of the page to pick and share the side you would pick if you were Pochettino on Tuesday.
Our unique algorithm has predicted the starting XI it believes is most likely to start, but you can also give it a go yourself.
Just click ‘create your own’ on the lineup at the top of the page and pick the XI players you would choose, and you can also see their stats per 90 minutes once you’ve picked them.
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