The Reds pursued the Netherlands international throughout the summer but Southampton stood firm, threatening to report Liverpool to the Premier League over an illegal approach.
It seems more than likely the Merseysiders will renew their interest in the former Celtic defender, either in January or next summer, but for now he remains a Southampton player.
Van Dijk is not the only Saints employee with Liverpool connections either. Head coach Mauricio Pellegrino spent six months at the club as a player under Rafael Benítez in 2005, making 12 league appearances before moving to Alavés where he started his coaching career.
Pellegrino only has one injury worry to contend with on Saturday as summer signing Mario Lemina is a doubt with an ankle problem. The Gabonese has been a shining light for the Saints in an otherwise forgettable campaign so far but missed the 1-0 home defeat by Burnley prior to the international break.
Our unique algorithm has predicted the Saints side it believes is most likely to start, but you can also give it a go yourself.
Just click ‘create your own’ on the lineup at the top of the page and pick the XI players you would choose, and you can also see their stats per 90 minutes once you’ve picked them.
When you’re happy with your team, press confirm and you’ll be able to share it with your friends via social media.