The Magpies, who clinched promotion from the Championship last season, currently sit in seventh position in the top flight and have taken an impressive 14 points from nine games this season.
Their Clarets, meanwhile, are punching well above their weight this term. Sean Dyche's side in eighth after claiming 13 points from their nine matches.
In their last meeting, Newcastle recorded a 3-3 draw with Burnley. Given the two sides are known for their defensive solidity, you doubt a repeat scoreline is on the cards.
Our unique algorithm has predicted the Newcastle United side it believes is most likely to start.
Football Whispers uses data to predict the starting line-ups for sides by accounting for a number of different factors, including injuries, suspensions, the statistical likelihood to play, the match the competition is played, the player’s previous performance and the style of the opposition.
But you can also give it a go yourself. Just click ‘create your own’ on the line-up at the top of the page and pick the XI players you would choose, and you can also see their stats once you’ve picked them.