The Foxes go into the game on Friday in 12th, but a win could see them rise to ninth.
Their opponents are in the relegation zone and also have a new manager in David Moyes, who lost his first match in charge of the Hammers last weekend.
Puel has a nearly fully-fit squad to pick from, with only Matty James (achilles) and Robert Huth (ankle) ruled out. Everyone else is available.
They’ll be hoping for a repeat of last season’s result, when they won 3-2 in East London.
Kick-off at the London Stadium is at 8pm, and the game is being shown live on Sky Sports.
Our unique algorithm has predicted the starting XI it believes is most likely to start, but you can also give it a go yourself.
Just click ‘create your own’ on the lineup at the top of the page and pick the XI players you would choose, and you can also see their stats per 90 minutes once you’ve picked them.
When you’re happy with your team, press confirm and you’ll be able to share it wth your friends via social media.