The Blaugrana were disappointing at the weekend, needing a late goal from Munir to draw 1-1 with Athletic Club.
Leo Messi started that game on the substitutes' bench but he will be back in the starting XI against Spurs and will be looking to build on the hat-trick he scored on match-day one.
Samuel Umtiti will miss the game due to injury and Sergi Roberto will also be absent.
Our unique algorithm has predicted the Barcelona side it believes will start the game.
Football Whispers uses data to predict teams’ starting XIs, taking into account injuries, suspensions, and the statistical likelihood of a player being selected. The widget can also show you players' recent form and stats.