José Mourinho's men have impressed in their opening two fixtures of the 2017/18 campaign, seeing off both West Ham United and Swansea City 4-0 and looking every bit genuine title contenders.
There is a long way to go yet, though, and the 2015/16 champions represent United's sternest test to date, having themselves looked in fine shape against Arsenal (an unfortunate 4-3 defeat) and Brighton & Hove Albion (a comfortable 2-0 win).
Our unique Predictive Line-ups algorithm takes into account injuries, suspensions, form and recent game time to predict how each Premier League team will line up, and here's how we think United will look on Sunday.
You can use the interactive graphic to select your own starting XI, view stats and share your team with friends via social media. Fancy yourself as the next Mourinho? Give it a try.
The Portuguese coach named an unchanged line-up for the first time in almost a year for his side's trip to the Liberty Stadium lat week, and the emphatic victory will have given him little cause to mix things up against the Foxes.
However, the fine form of Anthony Martial, who has twice come of the bench to score this season, will be giving Mourinho somewhat of a selection headache. The 21-year-old France international has looked superb and, crucially, newly motivated when making his cameos thus far and is deserving of a starting berth.
With the international break on the horizon, Mourinho will be keen to take full advantage of the momentum his side have built up in recent weeks to secure another three points, ensuring United remain at least two points clear of all their expected title rivals.