Usually the Reds would be fearing Pep Guardiola's attacking line up, but Jürgen Klopp will be hoping Virgil van Dijk can steady the ship?
He will certainly hope so after they got taken apart 5-0 at the Etihad back in September.
City saw a late Sergio Agüero goal give them a 2-1 advantage ahead of their second leg semi-final Carabao Cup tie against Bristol City and the league leaders will be confident of getting the job done at Ashton Gate, meaning they will be at full strength for Anfield.
Our unique algorithm has predicted the Manchester City side it believes will start the game.
Football Whispers uses data to predict teams’ starting XIs, taking into account injuries, suspensions, the statistical likelihood of a player being selected, the competition the match is in, players’ previous performances and the opponent’s style.
And you can also give it a go yourself. Just click ‘create your own’ on the line-up at the top of the page and pick your ideal XI for the game.You can also see each player’s stats once you’ve selected them.
When you’re happy with your team, press confirm and you’ll be able to share it with your friends via social media.