The Cherries currently sit in 19th position in the top flight and have taken just four points from their opening games this season. Their opponents, meanwhile, are in third place after claiming 14 points from their seven matches.
Eddie Howe will be hoping last season's top scorer Josh King recovers from a slight hamstring problem while Ryan Fraser (hamstring) is also a doubt.
Tyrone Mings (back), Adam Federici (knee) and Brad Smith (hip) are expected to miss the clash but striker Callum Wilson could return to the squad after he scored twice for the club's Under-21 side on Tuesday.
In their last meeting, Bournemouth were beaten 4-0 by Tottenham Hotspur. The Cherries will be will be looking to avenge that defeat this time around.
But who should start against Spurs? Our unique algorithm has predicted the Bournemouth side it believes is most likely to start, but you can also give it a go yourself.
Just click ‘create your own’ on the lineup at the top of the page and pick the XI players you would choose, and you can also see their stats per 90 minutes once you’ve picked them.
When you’re happy with your team, press confirm and you’ll be able to share it with your friends via social media.